Anest. intenziv. Med. 2015;26(4):213-219
Results of ECMO therapy in cohorts of neonates and childrenIntensive Care Medicine - Original Paper
- 1 Klinika dětského a dorostového lékařství VFN a 1. LF UK
- 2 II. interní klinika - klinika kardiologie a angiologie VFN a 1. LF UK
- 3 II. chirurgická klinika kardiovaskulární chirurgie VFN a 1. LF UK
- 4 Klinika kardiovaskulární chirurgie 2. LF UK a FN Motol
Objective:
Retrospective evaluation of a sample of 21 neonates and children treated with ECMO.
Design:
Observational, retrospective with prospective data collection.
Setting:
Paediatric and neonatal intensive care unit of a teaching hospital.
Materials and methods:
Between October 2010 and present, extracorporeal membrane oxygenation support was initiated in 21 patients based on meeting the indication criteria (12 neonates, 9 children). According to the etiology and severity of the cardiorespiratory failure, veno-arterial (V-A) ECMO was indicated in 57% of the patients (83% of the neonates, 22% of the children) - the remaining patients were treated with veno-venous (v-V) ECMO.
Results:
The survival rate was 58% in the neonatal group and 77% among the children. This work contains a brief comparison with some results of other international studies. Due to sample size, no statistical evaluation was performed.
Conclusion:
The authors demonstrate on the published sample that provision of the discussed care is neededin the Czech Republic. Many parameters of the presented outcomes are - in spite of the small sample size - comparable with the outcomes of the international registry.
Keywords: extracorporeal membrane oxygenation; respiratory failure; circulatory failure; neonate; paediatrics
Received: February 18, 2015; Accepted: April 3, 2015; Published: August 1, 2015 Show citation
References
- Hill, J. D., Bramson, M. L.,Gerbode, F.,Osborn, J. J., et al. Prolonged Extracorporeal Oxygenation for Acute Posttraumatic Respiratory Failure (Shock-Lung Syndrome) - Use of Bramson Membrane Lung. New England Journal of Medicine,1972, 286, p. 629.
Go to original source...
Go to PubMed...
- Bartlett, R. H., Gazzaniga, A. B., Jefferies, M. R., Huxtab-le, R. F., et al. Extracorporeal Membrane Oxygenation (Ecmo) Cardiopulmonary Support in Infancy. Transactions American Society for Artificial Internal Organs, 1976, 22, p. 80-93.
Go to PubMed...
- Extracorporeal Life Support Organization: ECLS Registry Report.Ann Arbor, MI, Extracorporeal Life Support organiza-tion 2012.
- Wernovsky, G., Wypij, D., Jonas, R. A., Mayer, J. E., et al. Postoperative Course and Hemodynamic Profile after the Arterial Switch Operation in Neonates and Infants - a Comparison of Low-Flow Cardiopulmonary Bypass and Circulatory Arrest. Circulation, 1995, 92, p. 2226-2235.
Go to original source...
Go to PubMed...
- Gaies, M. G., Gurney, J. G., Yen, A. H., Napoli, M. L., et al. Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatric Critical Care Medicine, 2010, 11, p. 234-238.
Go to original source...
Go to PubMed...
- Mugford, M., Elbourne, D., Field, D. Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. Cochrane Database of Systematic Reviews, 2008.
Go to original source...
- Zabrocki, L. A., Brogan, T. V., Statler, K. D., Poss, W. B., et al. Extracorporeal membrane oxygenation for pediatric respiratory failure: Survival and predictors of mortality. Critical Care Medicine, 2011, 39, p. 364-370.
Go to original source...
Go to PubMed...
- Skinner, S. C., Iocono, J. A., Ballard, H. O., Turner, M. D., et al. Improved survival in venovenous vs venoarterial extracorporeal membrane oxygenation for pediatric noncardiac sepsis patients: a study of the Extracorporeal Life Support Organization registry. Journal of Pediatric Surgery, 2012, 47, p. 63-67.
Go to original source...
Go to PubMed...
- Rehder, K. J., Turner, D. A., Cheifetz, I. M. Extracorporeal Membrane Oxygenation for Neonatal and Pediatric Respiratory Failure: An Evidence-Based Review of the Past Decade (2002-2012). Pediatric Critical Care Medicine, 2013, 14, p. 851-861.
Go to original source...
Go to PubMed...
- Cengiz, P., Seidel, K., Rycus, P. T., Brogan, T. V., et al. Central nervous system complications during pediatric extracorporeal life support: Incidence and risk factors.Critical Care Medicine, 2005, 33, p. 2817-2824.
Go to original source...
Go to PubMed...
- Guner, Y. S., Khemani, R. G., Qureshi, F. G., Wee, C. P., et al.Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenation. Journal of Pediatric Surgery. 2009, 44, p. 1691-1701.
Go to original source...
Go to PubMed...
- Rollins, M. D., Yoder, B. A., Moore, K. R., Barnhart, D. C., et al.Utility of neuroradiographic imaging in predicting outcomes after neonatal extracorporeal membrane oxygenation. Journal of Pediatric Surgery, 2012, 47, p. 76-80.
Go to original source...
Go to PubMed...
- Brogan, T. V., Zabrocki, L., Thiagarajan, R. R., Rycus, P. T.,et al. Prolonged extracorporeal membrane oxygenation for children with respiratory failure. Pediatric Critical Care Medicine, 2012, 13, E249-E254.
Go to original source...
Go to PubMed...
- Reed, R. C., Rutledge, J. C. Laboratory and Clinical Predictors of Thrombosis and Hemorrhage in 29 Pediatric Extracorporeal Membrane Oxygenation Nonsurvivors. Pediatric and Developmental Pathology, 2010, 13, p. 385-392.
Go to original source...
Go to PubMed...
- Machin, D., Scott, R., Hurst, A. Ground transportation of a pediatric patient on ECMO support. J. Extra Corpor. Technol., 2007, 39, p. 99-102.
Go to original source...
Go to PubMed...
- Coppola, C. P., Tyree, M., Larry, K., Digeronimo, R. A 22-year experience in global transport extracorporeal membrane oxygenation. J. Pediatr. Surg., 2008, 43, p. 46-52, discussion p. 52.
Go to original source...
Go to PubMed...
- Foley, D. S., Pranikoff, T., Younger, J. G., Swaniker, F., et al.A review of 100 patients transported on extracorporeal lifesupport. ASAIO J., 2002, 48, p. 612-619.
Go to original source...
Go to PubMed...