Anest. intenziv. Med. 2007;18(2):65-72

The benefits of BIS monitoring during sevoflurane anaesthesia in childrenAnaesthesiology - Original Paper

J. Capková, B. Komanová, K. Spodník, J. Firment

1. klinika anestéziológie a intenzívnej medicíny, LF UPJŠ a FNLP Košice, Slovenská republika

Objective:
To compare BIS values during standardized sevoflurane anaesthesia in children with end-tidal sevoflurane concentration, haemodynamic parameters and the speed of recovery.

Design:
Clinical prospective observational study.


Setting:
Department of Anaesthesiology and Intensive Medicine, Faculty of Medicine of P. J. Šafárik University, Košice, Slovakia.

Materials and methods:
96 children scheduled for elective surgery under general anaesthesia were included in the study. They were divided into 2 age groups (1-3 and 3-15 years of age). The anaesthesia protocol included i.v. induction and maintenance with sevoflurane. Sevoflurane concentration was adjusted according to MAC, movement to painful stimuli and vegetative signs.

Results:
In both the age groups BIS values showed a correlation with end-tidal sevoflurane concentration (r= -0.51-0.58, p < 0.01). In the 3-15yrs group there was a correlation between sevoflurane concentration and MAP (r= -0.45, p < 0.01). In both the age groups the times till awakening were significantly longer in the subgroup of children with perioperative BIS < 60 compared to the subgroup with BIS > 60 (age group 1-3 yrs: 45.8 ± 27 min vs. 35.1 ± 23 min, p < 0.05, age group 3-15yrs: 40.8 ± 17 vs. 18.1 ± 12 min, p < 0.001).

Conclusion:
In children aged 1-15 years of age the end-tidal concentration of sevoflurane correlated closer with BIS than with MAP and did not correlate with the heart rate. Children with perioperative BIS < 60 awakened later than children with BIS > 60.

Keywords: paediatric anaesthesia; bispectral index; sevoflurane

Published: April 1, 2007  Show citation