Čekání na nového šéfredaktora - jde o mnohem více než jen o správnou osobu...Editorial

Vladimír Černý

Anest. intenziv. Med. 2016;27(2):69-70  

Malignant hyperthermiaAnaesthesiology - Review articles

T. Vymazal

Anest. intenziv. Med. 2016;27(2):71-74  

Malignant hyperthermia is a rare, life-threatening condition, usually triggered by exposure to certain drugs used for general anaesthesia - specifically volatile anaesthetics (halothane, isoflurane, sevoflurane) and neuromuscular blocking agents (esp. suxamethonium). In susceptible individuals, these drugs can induce a drastic and uncontrolled increase in oxidative metabolism in the skeletal muscle leading to muscle rigidity, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide and regulate body temperature, eventually leading to circulatory collapse and death if not immediately treated. This review article brings information...

The role of antithrombin and thromboelastography in the management of early disseminated intravascular coagulopathy following peripartum hysterectomyAnaesthesiology - Case Reports

M. Durila, L. Teslík, M. Astraverkhava, T. Vymazal

Anest. intenziv. Med. 2016;27(2):75-77  

Disseminated intravascular coagulopathy is a life threatening condition, which can develop after hysterectomy performed because of peripartum life threatening bleeding in pregnant women. We present a case report where the laboratory and thromboelastography results indicating consumptive coagulopathy improved after the administration of antithrombin alone. In this case report we can see that antithrombin can help in the treatment of consumptive coagulopathy when administered at the right moment. Thromboelastography can be used for the diagnosis and monitoring of coagulopathy but it is also necessary to determine the antithrombin level because the same...

Current opinion on caudal epidural blockade and its complications in childrenDětská anesteziologie a intenzivní medicína

J. Šípek, V. Mixa

Anest. intenziv. Med. 2016;27(2):78-86  

Caudal block is a type of neuroaxial block (single shot or continuous), in which the local anesthetic is injected through the sacrococcygeal membrane into the caudal epidural area of the spinal canal. It provides analgesia which is important not just in the perioperative but mainly in the postoperative period. The single shot technique is more commonly used in paediatric anesthesia especially due to its very simple performance and low occurrence of complications. The complications include failure, infection or adverse effects of the local anaesthetics or their additives.The continuous caudal block has higher occurrence of complications caused by...

Sleep disturbances in perioperative and ICU patients - reviewIntesive Care Medicine - Review Article

L. Růžek, I. Čundrle ml.

Anest. intenziv. Med. 2016;27(2):87-97  

Sleep is an important part of human life. Loss of sleep (sleep deprivation) may have important implications on human organism. The perioperative period and ICU stay are associated with multiple factors causing changes in sleep length and architecture. The resulting effect and sleep pattern seem to be very similar to sleep-deprived patients. Surgical and critically ill patients may suffer from sleep disorders a few days after surgery or discharge from the ICU because of a rebound phenomenon of rapid eye movement and slow-wave sleep, which may be associated e.g. with obstructive sleep apnoea and/or delirium onset.

Alarmins and their role in perioperative medicineIntesive Care Medicine - Review Article

J. Máca

Anest. intenziv. Med. 2016;27(2):98-106  

Alarmins are mostly protein-based substances which, under normal conditions, are localized intracellularly, fulfilling their physiological functions. Currently, the most studied group of alarmins consists of the high-mobility group box 1, heat-shock proteins, proteins S100A, mitochondrial DNA and formylated methionine-leucyl-phenylalanine. In pathological condition, alarmins are released or actively secreted into the extracellular space where they presumably play an important role in activation of innate immunity. A wide spectrum of alarmins has been identified. Alarmins were studied in several chronic diseases during the last decades but there is...

Intravenous fluid therapy in intensive careIntesive Care Medicine - Review Article

J. Beneš

Anest. intenziv. Med. 2016;27(2):107-115  

Fluid therapy is an everyday issue in the daily routine of every anaesthesiologist and intensive care physician. Like with any other drug, administration of intravenous fluids is coupled with effects wanted and unwanted. This review article is a printed supplement and explanation of the electronic Smart Card issued for better understanding of how and when fluids should be indicated and administered.

Jak poznat, že EKG je abnormální a co nám zobrazuje standardní EKG záznamPostgraduální vzdělávání - EKG v klinické praxi

J. Jakabčin

Anest. intenziv. Med. 2016;27(2):116-120  

Anestezie v onkochirurgiiPostgraduate Education - Topics for Board Examination

V. Černý

Anest. intenziv. Med. 2016;27(2):121-122  

Practice Guidelines for the Prevention, Detection, and Management of Respiratory Depression Associated with Neuraxial Opioid Administration: An Updated Report by the American Society of Anesthesiologists Task Force on Neuraxial Opioids and the American Society of Regional Anesthesia and Pain MedicineGuidelines

V. Černý

Anest. intenziv. Med. 2016;27(2):123-125  

The Spireta ProjectHistory

J. Vetešník

Anest. intenziv. Med. 2016;27(2):126-130  

Spireta laid the foundation for mobile ventilation equipment for resuscitation in Czechoslovakia in the late 1970s and 80s. The first version of the apparatus was made for military use (1977). It worked on the proven principle of intermittent positive pressure using O2 as the driving medium and featured original, reliable mechanical devices for the timing of the respiratory phases (Czechoslovak patent by Ing. Rumánek and his technician Sláma, 1976). It was manufactured by the Chirana company based in Stará Turá. The emergency services (briefcase) version weighed 15 kg and allowed mechanical ventilation and oxygen inhalation by face mask. It also included...

Odmítání transfuzních přípravků pacientem - odpovědi na dotazy čtenářůEthics and Medicine Law

R. Černá Pařízková, J. Mach

Anest. intenziv. Med. 2016;27(2):131-134  

Rady kolegům ve specializačním vzdělávání a informace ze Specializační oborové rady (SOR) oboru anesteziologie a intenzivní medicína (AIM)News from CSARIM

Michal Horáček

Anest. intenziv. Med. 2016;27(2):136-137