Anesteziologie a intenzivní medicína, 2004 (vol. 15), issue 6
The Impact of Different Rocuronium Doses on its Pharmacodynamic Profile:a Prospective StudyArticles
M. Adamus, R. Bělohlávek, M. Vujčíková, E. Janásková
Anest. intenziv. Med. 2004;15(6):269-275
Objective:The aim of the study was to assess rocuronium pharmacodynamics following a single bolus dose.Design: Clinical prospective randomized controlled study.Setting: Department of Anaesthesiology and Intensive Care, University Hospital.Material and Methods: Following the ethics committee approval and obtaining informed consent 210 patients scheduled forelective surgery under general anaesthesia with tracheal intubation were randomized into 7 groups with different rocuroniumdoses administered (0.30, 0.45, 0.60, 0.75, 0.90, 1.05, 1.20 mg*kg-1, respectively). After setting up neuromusculartransmission monitoring (Datex-Ohmeda S5 Anaesthesia...
Efficacy and Safety of Levobupivacaine: a Multicenter Survey NORA (New Regional Anaesthetic)Articles
M. Horáček, P. Michálek, D. Mach, D. Miloschewsky
Anest. intenziv. Med. 2004;15(6):279-284
Objective:To investigate the efficacy and safety of levobupivacaine, a new local anaesthetic associated with a low frequencyof toxicity in an everyday clinical practice.Design: Open-label prospective questionnaire survey.Setting: Departments of anaesthesiology in 57 hospitals in the Czech Republic.Material and Methods: 3325 patients aged 2-97 years operated in regional or combined anaesthesia with levobupivacaineor with an obstetric analgesia between May and December 2003. Participating anaesthesiologists filled data in datacollection sheets. Reported data were centrally loaded into the NORA database and processed. The efficacy of levobupivacainewas...
Deaths during Operations and in the Postoperative Period: 155 260 Anaesthetics Administeredin Motol University Hospital Prague during 1999-2003Articles
K. Cvachovec, M. Filaun
Anest. intenziv. Med. 2004;15(6):285-290
Objective:Analysis of the deaths during operations - mors in tabula - during 1999-2003 and evaluation of the deaths during24 hours following anaesthesia during 2000-2003.Design: Retrospective observational study.Setting:Department of Anaesthesiology and Intensive Care Medicine of Charles University, 2th Medical Faculty and Institutefor Further of Health Professionals in University Hospital, Prague-Motol.Material and Method:The database of complicationwas used to supply demographic data, theASAclass,type of anaesthesiaand character of the operation (elective or urgent). Peroperative mortality, mortality during 24 hours after anaesthesia andoverall...
Obstetric Analgesia and Anaesthesia in the Czech Republic in 2002Articles
A. Pařízek
Anest. intenziv. Med. 2004;15(6):291-293
Objective:Nationwide study on the current level and frequency of methods of analgesia in labour, the psychological andorganisation set up of delivery and the feasibility of near relatives (fathers) to participate at delivery and obstetric operations.Design: Annual questionnaire survey (2002) from obstetric and anaesthesiologic departments in the Czech Republic.Setting: Department of Gynaecology and Obstetrics, University Hospital, Praque.Material and Methods: Women at obstetric departments having delivered their babies in the Czech Republic from January1st to December 31st 2002.Results: The majority of deliveries (82.1%) have been performed...
Complications of the Percutaneous Dilatational Tracheostomy and Surgical Tracheostomy. Are Both Methods Equally Safe?Articles
P. Matoušek, K. Pokorný, J. Mejzlík, J. Matyáš, J. Chalupa
Anest. intenziv. Med. 2004;15(6):294-298
Objective:Comparison of complications of percutaneous (PDT) and surgical tracheostomies (ST).Design: Retrospective study.Setting: Department of ENT and Department of Anaesthesiology and Intesive Care, Hospital Frýdek-Místek, Department ofENT and Department of Anaesthesiology and Intensive Care, Hospital Pardubice.Material and Method: Retrospective study of patients, who underwent tracheostomy in hospitals Frýdek-Místek andPardubice from 1998 to 2002 was conducted. The incidence of early and late complications of PDT and ST was observed.The relation of complications and techniques and also between complications and timing of ST was observed....
A Bit of History on Physostigmine and Its Use in PragueArticles
B. Dvořáček, J. Rupreht
Anest. intenziv. Med. 2004;15(6):299-302
In the 1860s, the extract of the Calabar bean or Esére nutwasstudied as a poison butwasalso introduced into ophthalmologyas an antagonist for atropine. Kleinwächter in Prague described it in 1864 as a succesful and specific antidote for atropinepoisoning. Several decades passed before physostigmine was isolated, but this substance has remained famous becauseit enabled discovery and establishment of neurotransmission, which started with the discovery of muscarinic action ofacetylcholine. The anti-curare properties of physostigmine were demonstrated in 1900 by Pal. However, when curare was atlast introduced into clinical anaesthesia in 1942, the antagonist...