Anest. intenziv. Med. 1999;10(3):120-122

The role of immunologic diagnostics in ICUArticles

M. Průcha, M. Dostál, B. Kavka1
OKBHI Nemocnice Na Homolce, primář prof. MUDr. J. Hyánek, DrSc.
1 ARO Nemocnice Na Homolce, primář MUDr. M. Ročeň

Patients hospitalized in ICUs for sepsis create a heterogenic group in which marked interindividual differences could be found in immune responseto infectious agents or traumatic insult. Dysfunction of humoral and cellular immunity is well marked. The evaluation of selected parameters of humoraland cellular immunity provides us with information on immune response competence and plays a key role in decision making process regarding theuse of immunomodulation therapy. There can be a major differences according to the actual state of immune system. The paper presents the authors'own experience with evaluation of the importance of phenotype marks expression in lymphocytes and monocytes in patients with clinical picture ofsepsis related to 28-day mortality. The authors discuss the importance of selected tests for further therapeutic immunomodulatory treatment.

Keywords: sepsis; flow cytometry; inflammation; immunomodulation

Published: June 1, 1999  Show citation

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Průcha M, Dostál M, Kavka B. The role of immunologic diagnostics in ICU. Anest. intenziv. Med. 1999;10(3):120-122.
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