Role recenzentů - nenahraditelná, ale bohužel neviditelná…

prof. MUDr. Vladimír Černý, Ph.D., FCCM, FESAIC, doc. MUDr. Jiří Málek, CSc.

Anest. intenziv. Med. 2024;35(2):85-86  

Management of patients with trauma in the Czech Republic - results of a questionnaire study across 12 trauma centers for adults

Holubová G., Vymazal T., Beitl E., Dráč P., Edelmann K., Gürlich R., Jícha Z., Kloub M., Kočí J., Krtička M., Menšík P., Pavelka T., Matějka J., Pleva L., Šír M., Šrám J., Durila M.

Anest. intenziv. Med. 2024;35(2):89-97 | DOI: 10.36290/aim.2024.020  

Despite the existence of many guidelines in the management of trauma, trauma is still the leading cause of death in young age groups, and mortality has not decreased in the Czech Republic over the past 10 years. The issues of circulatory stability, indications for the administration of whole blood, routine use of imaging methods, and prioritization of individual care steps are still not clearly defined. We decided to use a questionnaire study to map what the initial care of traumatized patients looks like across our country in 12 trauma centers and to define the circulatory stability of the patient, on which the sequence of individual diagnostic and...

Pathogenesis of euglycemic ketoacidosis associated with SGLT2 inhibitors

Šitina M., Šrámek V.

Anest. intenziv. Med. 2024;35(2):98-103 | DOI: 10.36290/aim.2024.018  

Euglycemic ketoacidosis associated with SGLT2 inhibitors, also referred to as gliflozins, is a rare but potentially fatal clinical entity characterized by metabolic acidosis with normal or only mildly elevated glycemia, predominantly in patients with type 2 diabetes mellitus. In addition to ketoacidosis, hyperchloremic acidosis may also contribute significantly to metabolic acidosis. Relative hypoglycemia induced by gliflozins and concomitant stress condition lead to decreased insulin level and increased glucagon, cortisol, and catecholamines, which stimulates ketogenesis. At the same time, gliflozins induce complex renal metabolic dysfunction, in...

Management of amniotic fluid embolism

Pešková K., Štourač P., Seidlová D.

Anest. intenziv. Med. 2024;35(2):104-115 | DOI: 10.36290/aim.2024.023  

Amniotic fluid embolism is characterized by sudden cardiorespiratory collapse during labor or soon after delivery. We present immediate management when a rapid response is critical. The appearance of disseminated intravascular coagulation confirms high suspicion of the diagnosis plausibly. We remind administration of tranexamic acid and fibrinogen. Fibrinogen is preferred over plasma to minimize the risk of volume overload. Avoidance of fluid overload is an important management principle of pulmonary hypertension and right heart failure. Inotropes and pulmonary vasodilators are the mainstays of therapy. Although the therapeutic application of C1 esterase...

Euglycemic ketoacidosis associated with SGLT2 inhibitors and DPP4 inhibitors - discussion of case reports

Šitina M., Šrámek V.

Anest. intenziv. Med. 2024;35(2):116-121 | DOI: 10.36290/aim.2024.019  

Euglycemic ketoacidosis is a rare but potentially fatal complication of treatment with SGLT2 inhibitors (gliflozins). However, similar euglycemic ketoacidosis may rarely occur with other antidiabetic drugs or conditions such as pregnancy or alcohol abuse. We describe 3 cases of our patients with euglycemic ketoacidosis associated with gliflozins and 1 case associated with the DPP4 inhibitor sitagliptin and discuss in detail the acid-base disturbances present and the distinction of euglycemic ketoacidosis from classical ketoacidosis in type 1 diabetes.

Alois Alzheimer: lékař, na kterého se zapomíná

Málek J.

Anest. intenziv. Med. 2024;35(2):125-126 | DOI: 10.36290/aim.2024.017  

Použití plné krve u pacientů se život ohrožujícím krvácením v důsledku traumatu: souhrn a konsenzus jednání mezioborového panelu

Bláha J., Bohoněk M., Černý V., Klugar M., Kočí J., Loužil J., Řeháček V., Truhlář A., Zýková I.

Anest. intenziv. Med. 2024;35(2):127-130 | DOI: 10.36290/aim.2024.022  

Klinická fyziologie respiračního systému a patofyziologie hyperkapnie

Řehák D., Astapenko D., Černý V.

Anest. intenziv. Med. 2024;35(2):122-124 | DOI: 10.36290/aim.2024.026  

Komentář k článku: Použití plné krve u pacientů se život ohrožujícím krvácením v důsledku traumatu: souhrn a konsenzus jednání mezioborového panelu

Blatný J.

Anest. intenziv. Med. 2024;35(2):131  

Komentář k článku: Použití plné krve u pacientů se život ohrožujícím krvácením v důsledku traumatu: souhrn a konsenzus jednání mezioborového panelu

Lejdarová H.

Anest. intenziv. Med. 2024;35(2):132  

Bronchoskopie jednorázovými endoskopy

Votruba J., Otáhal M., Balík M.

Anest. intenziv. Med. 2024;35(2):133-135 | DOI: 10.36290/aim.2024.024