Editorial

doc. MUDr. Jiří Málek, CSc.

Anest. intenziv. Med. 2022;33(2):67  

Aktualizovaná doporučení pro léčbu akutní pooperační bolesti - důvod pro "inventuru" vlastní i institucionální praxe?

prof. MUDr. Vladimír Černý, Ph.D., FCCM

Anest. intenziv. Med. 2022;33(2):68 | DOI: 10.36290/aim.2022.015  

Up-to-date diagnosis and treatment of anaphylactic reaction

Keller F., Kratochvíl M., Maláska J.

Anest. intenziv. Med. 2022;33(2):71-78 | DOI: 10.36290/aim.2021.053  

The article summarizes up-to-date knowledge about effective diagnosis and treatment of anaphylactic reaction. It covers management of the acute anaphylactic reaction within the scope of emergency medicine, with special focus on the usage of intramuscularly injected adrenaline. Topics such as testing for allergies or the specific patophysiology of the anaphylaxis are not emphasized. The article is based on up-to-date guidelines and additional scientific evidence. Knowledge about the etiology and the risk factors is essential when diagnosing anaphylaxis. The diagnosis itself is based on the case circumstances, patients medical history and a physicians...

Monitoring of processed EEG under anesthesia I

Horáček M.

Anest. intenziv. Med. 2022;33(2):79-89 | DOI: 10.36290/aim.2022.012  

The target organ of most substances applied during general anesthesia is the brain. The manifestations of its function include, above all, consciousness. It is associated with the electrical activity of neurons, which can be easily recorded from the surface of the skull - electroencephalography (EEG). The electrical activity of the brain in anesthesia changes in a predictable way depending on the anesthetic used and its dose. EEG assessment is difficult but has been greatly simplified by computer development. Therefore, computer-processed EEG (pEEG) may soon become an integral part of monitoring patients under anesthesia. Anesthesiologists' attention...

Cytokine release syndrome after CAR T-cell therapy: a review of the literature and our experience

Čemusová B.

Anest. intenziv. Med. 2022;33(2):90-96 | DOI: 10.36290/aim.2022.013  

Cytokine release syndrome is an acute systemic inflammatory response triggered by overactivation of the immune system that may be initiated by a variety of factors. The incidence of cytokine release syndrome is high, especially after immunotherapy with chimeric antigen receptor T-cells, which is effective for refractory or recurrent B cell hematological malignancies. Cytokine release syndrome occurs due to a high level of immune activation of lymphocytes, macrophages, or myeloid cells with a subsequent massive release of inflammatory cytokines. After chimeric antigen receptor T-cell therapy, symptoms appear within days of infusion, which correlates...

Awareness during surgery and anesthesia

Málek J.

Anest. intenziv. Med. 2022;33(2):97-100 | DOI: 10.36290/aim.2022.007  

This case report describes a retrospective case of awareness during anesthesia, the consequences of which are still manifested 35 years after the event. Although this complication is rare, it can have long-term effects. An overview of the incidence, risk factors, prevention options, and what to do if awareness during aaesthesia occurs is presented.

Rhabdomyolysis

Černý V.

Anest. intenziv. Med. 2022;33(2):109-110 | DOI: 10.36290/aim.2022.018  

The concept of “Physiologically difficult airways” – it is not only about intubation

Astapenko D., Černý V.

Anest. intenziv. Med. 2022;33(2):101-102 | DOI: 10.36290/aim.2022.016  

Anaesthesia in the Austro-Hungarian Empire during World War I and in the newly formed Czechoslovak Republic. Part 5 - General anaesthesia II: methods and complications

Gimunová O., Málek J.

Anest. intenziv. Med. 2022;33(2):103-108 | DOI: 10.36290/aim.2022.017  

The authors present the commented part of a 1921 textbook of surgery, the first edition of which was published as a textbook in 1917. The introductory part of this historical publication is devoted to anesthesia and is surprising in its scope. Due to its size, the present text has been divided into 4 parts (Introduction, Local anesthesia, Intravenous regional anesthesia and neuroaxial blockade, General anesthesia I), which were already published in this journal in 2017-2018. After obtaining the rest of the text, we now publish the last part dedicated to the technique of performing anesthesia and to the management of complications, including resuscitation....

Features of interest, tips and tricks, information from other disciplines

Černý V.

Anest. intenziv. Med. 2022;33(2):121-122 | DOI: 10.36290/aim.2022.020  

Guidelines for acute postoperative pain therapy

Křikava I., Kubricht V., Lejčko J., Málek J., Ševčík P., Štourač P.

Anest. intenziv. Med. 2022;33(2):111-120 | DOI: 10.36290/aim.2022.019