Anest. intenziv. Med. 2019;30(3-4):153-161

Basic neuromodulation methods in chronic pain managementLéčba bolesti - přehledový článek

J. Kozák^1,*, Š. Kozák², I. Vrba³

¹ Centrum pro léčení a výzkum bolestivých stavů při Klinice rehabilitace a tělovýchovného lékařství, 2. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice v Motole

² Ambulance léčby bolesti, Klinika anesteziologie a resuscitace, 3. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady

³ Anesteziologicko-resuscitační oddělení, Nemocnice Na Homolce

Chronic pain is not always manageable with standard treatment modalities. Moreover, physicians are now globally on the constant lookout for opioid sparing in chronic pain management due to the "opioid crisis", and neuromodulation treatment may by the possible answer. Neuromodulation is the process of inhibition, stimulation, modification or therapeutic alteration of activity in the central or peripheral nerve systems, with the use of electric current or drugs. The most important parts of neuromodulation for pain management are neurostimulation and intrathecal drug delivery. The use of neuromodulation has evidently seen growth over the course of the last decade due to novel systems, hardware advancements, and novel chronic pain indications. In this article we present an updated review on spinal cord stimulation and intrathecal drug delivery systems, and their use in chronic pain treatment.

Keywords: chronic pain; treatment; neuromodulation; spinal cord stimulation; intrathecal drug delivery

Received: August 16, 2019; Accepted: September 19, 2019; Published: June 1, 2019  Show citation