Anest. intenziv. Med. 2017;28(2):80-84

Anaphylactic reaction to sugammadex administered at the end of surgeryAnaesthesiology - Case Reports

S. Palásková^1,*, H. Paříková¹, J. Vydláková², E. Uchytilová¹, E. Kieslichová¹

¹ Klinika anesteziologie, resuscitace a intenzivní péče, Institut klinické a experimentální medicíny Praha

² Pracoviště laboratorních metod - ambulantní a experimentální imunologie, Institut klinické a experimentální medicíny Praha

The possibility of rapid and predictable reversal of neuromuscular blockade induced by rocuronium or vecuronium leads to more frequent use of sugammadex in clinical practice. Sugammadex seems to be a safe and well tolerated medicament, which is available throughout the European Union. We noted a case of serious anaphylactic reaction after the administration of sugammadex, manifested by cardiovascular collapse. The situation required immediate initiation of fluid and pharmacological resuscitation. With this case report we would like to illustrate that even a generally safe medicament such as sugammadex may cause serious life-threatening complications.

Keywords: sugammadex; anaphylactic reaction; perioperative complication

Received: August 9, 2016; Accepted: November 21, 2016; Published: April 1, 2017  Show citation