Anest. intenziv. Med. 2008;19(3):149-153

Preventive measures of nosocomial infection in ventilated patients - current statusIntesive Care Medicine - Review Article

Stoszek Dalibor1,*, Dostál Pavel2, Vlková Andrea2
1 Neurochirurgická klinika, Univerzita Karlova v Praze, Lékařská fakulta v Hradci Králové Fakultní nemocnice Hradec Králové
2 Klinika anesteziologie, resuscitace a intenzivní medicíny, Univerzita Karlova v Praze Lékařská fakulta v Hradci Králové, Fakultní nemocnice Hradec Králové

Ventilator-associated pneumonia (VAP) is the most common ICU-acquired infection in patients requiring mechanical ventilation. VAP remains a leading cause of morbidity and mortality in mechanically ventilated patients and is associated with longer ICU and hospital stay, prolonged mechanical ventilation and increased costs. The aim of the article is to give a systematic review of evidence-based methods of VAP prevention, focused on new facts reported since 2006.

Keywords: ventilator-associated pneumonia; VAP; VAP prevention

Received: March 25, 2008; Accepted: March 31, 2008; Published: June 1, 2008  Show citation

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Stoszek D, Dostál P, Vlková A. Preventive measures of nosocomial infection in ventilated patients - current status. Anest. intenziv. Med. 2008;19(3):149-153.
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References

  1. Tablan, O., Anderson, L., Besser, R. et al. Guidelines for preventing health-care-associated pneumonia, 2003. Recommendations of CDC and the Healthcare Infection Control Practises Advisory Committee. MMWR Recomm. Rep., 2004, 53, (RR-3), p. 1-36.
  2. Iregui, M., Kollef, M. et al. Prevention of Ventilator - Associated Pneumonia. Chest, 2002, 121, p. 679-681. Go to original source... Go to PubMed...
  3. Niederman, M. S., Craven, S. E. et al. American Thoracic Society documents. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and health care associated pneumonia. Am. J. Resp. Crit. Care Med., 2005,171, p. 388-416. Dostupné na www: http://www.thoracic.org/adobe/statements/guide1-29.pdf. Go to original source... Go to PubMed...
  4. Gastmeier, P., Geffers, C. Prevention of ventilator-associated pneumonia: analysis of studies published since 2004. Journal of Hospital Infection, 2007. Dostupné na WWW: www.elsevierhealth.com/journals/jhin. Go to original source... Go to PubMed...
  5. Lorente, L., Lecuona, M., Alejandro, J. et al. Influence of an Endotracheal Tube with Polyurethane Cuff and Subglottic Drainage on Pnemonia. Am. J. Respir. Crit. Care Med., 2007, Sep. 13. Go to original source... Go to PubMed...
  6. Isakow, W., Morrow, L., Kollef, M. Probiotics for Preventing and Treating Nosocomial Infections, Review of Current Evidence and Recommendations. Chest, 2007, 132, p. 286 to 294. Go to original source... Go to PubMed...
  7. Chlebicki, M. P., Safdar, N. Topical chlorhexidine for prevention of ventilator-associated pneumonia: a metaanalysis, Crit. Care Med., 2007, 35, 2, p. 668-669. Go to original source... Go to PubMed...
  8. Chan, E. Y., Ruest, A., Meade, M., Cook, D. Oral decontamination for prevention of pneumonia in mechanically ventilated adults: systematic review and meta-analysis. BMJ, 2007, 334, p. 889. Go to original source... Go to PubMed...
  9. Senol, G., Kirakli, C. et al. In vitro antibacterial activities of oral care products against ventilator-associated pneumonia pathogens. Am. J. Infect. Control., 2007, 35, 8, p. 531-535. Go to original source... Go to PubMed...
  10. Minei, J., Nathens, A., West, M., Harbrecht, B. et al. II. Guidelines for Prevention, Diagnosis and Treatment of Ventilator-Associated Pneumonia (VAP) in the Trauma Pacient. J. Trauma, 2006, 60, p. 1106-1113. Go to original source... Go to PubMed...
  11. Seguin, P., Tanguy, M. et al. Effect of oropharyngeal decontamination by povidone-iodine on ventilator-associated pneumonia in patients with head trauma. Crit. Care Med., 2006, 34, p. 1514-1519. Go to original source... Go to PubMed...
  12. Dostál, P. et al. Základy umělé plicní ventilace. 2. rozšířené vydání, Praha: Maxdorf Jessenius 2005, s. 258-266.
  13. Irwin, R. S., Rippe, J. M. Irwin and Rippe's Intensive Care Mediciine, 6th edition, Lippincott Williams&Wilkins 2008, p. 822-847.
  14. Kishimoto, H., Urade, M. Mechanical Tooth Cleaning before Chlorhexidine Application. Am. J. Respir. Crit. Care Med., 2007. Go to original source... Go to PubMed...
  15. Jondergen, I., Rovers, M. et al. Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a systematic review and meta-analysis. Crit. Care Med., 2007, 35, p. 260-270. Go to original source... Go to PubMed...
  16. Valencia, M., Ferrer, M., Farre, R., Navajas, D., Badia, J. R., Nicolas, J. M., Torres, A. Automatic control of tracheal tube cuff pressure in ventilated patients in semicurbent position: a randomized trial. Crit. Care Med., 2007, 35, 6, p. 1543-1549. Go to original source... Go to PubMed...
  17. Hugonnet, S., Chevrolet, J.-C. The effect of workload on infection risk in critically ill patients. Crit. Care Med., 2007, 35, p. 76-81. Go to original source... Go to PubMed...
  18. Blot, S., Labeau, S. et al. Evidence-based guidelines for the prevention of ventilator-associated pneumonia: results of a knowledge test among intensive care nurses. Intensive Care Med, 2007, 33, p. 1463-1467. Go to original source... Go to PubMed...
  19. Omrane, R., Eid, J., Perreault, M. M. et al. Impact of a protocol for prevention of ventilator-associated pneumonia. Ann. Pharmacother., 2007, 41, 9, p. 1390-1396. (Roub. 2007 Aug 14) Go to original source... Go to PubMed...
  20. Koeman, M., van der Ven, A., Hak, E. et al. Oral decontamination with chlorhexidine reduces incidence of ventilátor ssociated pneumonia. Am. J. Respir. Crit. Care Med., 2006, 173, p. 1348-1355. Go to original source... Go to PubMed...
  21. Cook, D. J., Walter, S. D., Cook, R. J. Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann. Intern. Med., 1998, 129, 6, p. 433. Go to original source... Go to PubMed...
  22. Cook, D., Guyatt, G., Marshall, J. et al. A Comparison of Sucralfate and Ranitidine fot the Prevention of Upper Gastrointestinal Bleeding in Patients Requiring Mechanical Ventilation. NEJM, 1998, 338, p. 791-797. Go to original source... Go to PubMed...
  23. Prod'hom, G., Leuenberger, P., Koerfer, J. et al. Nosocomial Pneumonia in Mechanically Ventilated Patients Receiving Antacid, Ranitidine, or Sucralfate as Prophylaxis for Stress Ulcer. A randomized controlled trial. Ann. Intern. Med., 1994, 120, p. 653-662. Go to original source... Go to PubMed...
  24. Sirvent, J. M., Torres, A. et al. Protective effect of intravenously administered cefuroxime against nosocomial pneumonia in pacients with structural coma. Am. J. Respir. Crit. Care Med., 1997, 155, p. 1729-1734. Go to original source... Go to PubMed...
  25. McClave, S. A., Lukan, J. K., Stefater, J. A.et al. Poor validity of residual volumes as a marker for risk of aspiration in critically ill patiens. Crit. Care Med., 2005, 33, p. 324-330. Go to original source... Go to PubMed...
  26. Sobotka, L., Allison, S. P., Meier, R. et al. Basics in clinical nutrition. Third Edition, Praha : Galén 2004.
  27. Van den Berghe, G., Wouters, P. J., Weekers, F. et al. Intensive insulin therapy in critically ill patiens. N. Engl. J. Med., 2001, 345, p. 1359-1367. Go to original source... Go to PubMed...
  28. Treggiari, M. M., Karir, V., Yanez, N. D. et al. Intensive insulin therapy and mortality in critically ill patiens. Crit. Care, 2008, 12, p. R29. Go to original source... Go to PubMed...




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