Anesteziologie a intenzivní medicína, 2006 (vol. 17), issue 3
A comparison of haemodynamic changes using thoracic epidural anesthesia versus standard balanced anaesthesia during on-pump coronary artery bypass graftingAnaesthesiology - Original Paper
M. Stříteský, D. Rubeš, M. Semrád, T. Čermák, M. Lipš
Anest. intenziv. Med. 2006;17(3):138-144 
Background:Thoracic epidural anaesthesia is a method with a short history starting in the early eighties. Its use in cardiac surgery patients is presumed to reduce peri-operative and early post-operative ischaemia, provide superior analgesia, shorten re-warming and extubation times and improve ventilation parameters. Materials and Methods:A total of 30 patients undergoing CABG under general anaesthesia were randomized to the thoracic epidural group (N = 15) and plain general anaesthesia group (N = 15).We observed haemodynamic parameters (HR, BP, CI, SVRI, LVSWI), markers of analgesia, extubation time, time till awake and early...
Assessment of performance of NMT stimulators used during anaesthesia in the Czech RepublicAnaesthesiology - Original Paper
M. Adamus, P. Adamus, R. Bělohlávek, M. Ludma, P. Hropko
Anest. intenziv. Med. 2006;17(3):145-155
Objective:To assess the performance of NMT stimulators used during anaesthesia in the Czech Republic. To test the ability of the stimulators to work as "constant-current generators". Design:Laboratory prospective controlled study Setting:Department of Anaesthesiology and Intensive Care, University Hospital and Palacky University, Olomouc. Materials and Methods:Six commercially available peripheral nerve stimulators were studied in laboratory settings. Each stimulator (single twitch mode, stimulating current 10, 20, 30, 40, 50 and 60 mA, respectively) was set to work at different loading resistance...
Optimization of the intravascular volume in multiple trauma patients using esophageal Doppler - preliminary resultsIntensive Care Medicine - Original Paper
I. Chytra, R. Pradl, R. Bosman, P. Pelnář, E. Kasal, A. Židková
Anest. intenziv. Med. 2006;17(3):156-163
Objective:The aim of study was to assess the effect of early optimization of intravascular volume using esophageal Doppler on blood lactate levels and organ dysfunction development in comparison with standard haemodynamic management in multiple trauma patients. Design:Prospective randomized controlled study. Setting:Interdisciplinary intensive care unit of a university teaching hospital. Materials and Methods:Multiple trauma patients with estimated blood loss of more than 2000 ml admitted to an interdisciplinary ICU were randomized to the protocol group with esophageal Doppler monitoring or the...
Analysis of the specificity and sensitivity of procalcitonin in relation to other markers of inflammation in critically ill patientsIntensive Care Medicine - Original Paper
J. Valenta, A. Jabor, H. Brodská, Z. Stach, A. Kazda, M. Stříteský
Anest. intenziv. Med. 2006;17(3):164-170
Objective:To evaluate the diagnostic specificity and sensitivity of procalcitonin (PCT) in comparison with C-reactive protein (CRP) and other inflammatory markers in relation to clinical status and microbiology examinations. Design:Prospective study in ICU patients. Setting:Department of Anaesthesiology and Intensive Care, University Hospital, 1st Medical Faculty, Charles University, Prague. Materials and Methods:164 examinations of PCT, CRP, orosomucoid, prealbumin, fibrinogen, INR, white cell and platelet count were evaluated in 43 patients. APACHE II was calculated on admission, SOFA daily....
Assessment of regional tissue perfusion by indicator microdialysis techniqueIntensive Care Medicine - Comprehensive Report
V. Černý, M. Šitina
Anest. intenziv. Med. 2006;17(3):171-175
Indicator microdialysis technique employs microdialysis for quantitative assessment of regional tissue perfusion. A special slim probe with a semi-permeable membrane at the tip is inserted into the tissue where small molecules are interchanged between the fluid inside the probe and the interstitial tissue. The indicator substance is supplied to the probe where it partly diffuses into the interstitial fluid and gets drawn into blood capillaries. In steady state diffusion of the indicator out of the probe is proportional to tissue perfusion. It is also influenced by many other factors such as tissue diffusibility of the indicator, intensity of probe...
Surfactant - use in adult patientsIntensive Care Medicine - Comprehensive Report
D. Romportl, A. Hodek, M. Krečmerová, M. Pelichovská, K. Cvachovec
Anest. intenziv. Med. 2006;17(3):176-180
Surfactant is a complex surface-active substance, consisting of lipids and proteins, which lines the surface of terminal bronchioles and alveoli of mammalian lungs. It is responsible for maintaining essential biophysical and immunological functions of the lungs. Surfactant impairment is common in many pathological situations, leading to deterioration of pulmonary function. These facts have been known for about 50 years and since then we have been trying to develop effective treatment based on a natural or synthetic surfactant. In clinical practice, the use of surfactant has been well established only in newborns. In adults, the greatest experience...