Anest. intenziv. Med. 2024;35(4):229-235 | DOI: 10.36290/aim.2024.028

Since when is salt acidic? Do we really understand hyperchloremic acidosis?Review Article

Šitina M.
Anesteziologicko-resuscitační klinika, FN u sv. Anny, Brno
Oddělení biostatistiky, International Clinical Research Center, FN u sv. Anny, Brno
Ústav patologické fyziologie, Lékařská fakulta, Masarykova univerzita, Brno

The article compares 2 perspectives on acid-base considerations. The formal view, of Stewart, is suitable for exact calculations, but less intuitively understandable, since it does not deal with the question of the internal mechanisms of acid-base processes, but suffices to satisfy formal physical-chemical laws. And the intuitive view, which provides a comprehensible qualitative idea of the direction, toward acidosis or alkalosis, in which acid-base will evolve. The article further explains the nature of dilutional and hyperchloremic acidosis and shows that not NaCl but water in solution is its cause.

Keywords: acid-base balance, Stewart, intuitive, hyperchloremic acidosis.

Received: April 21, 2024; Revised: June 18, 2024; Accepted: June 27, 2024; Prepublished online: September 4, 2024; Published: December 17, 2024  Show citation

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Šitina M. Since when is salt acidic? Do we really understand hyperchloremic acidosis? Anest. intenziv. Med. 2024;35(4):229-235. doi: 10.36290/aim.2024.028.
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