Anest. intenziv. Med. 2002;13(1):10-11

Changes in Cholesterol Metabolism within a Few Days tlfter Severe TraumaArticles

B. Bakalář1, Z. Zadák2, J. Pachl, R. Hyšpler1,2, J. Pažout1
Univerzita Karlova, Klinika anesteziologie a resuscitace 3. LF a FN Královské Vinohrady, Praha, přednosta doc. MUDr. Jan Pachl, CSc.
Univerzita Karlova, Klinika gerontologická a metabolická LF a FN Hradec Králové, přednosta prof. MUDr. Zdeněk Zadák,

We evaluated cholesterol and its precursors metabolism in 70 patiems within a few days after polytrauma. We observed low serum cholesterol levels (< 3.5 mmoUl) in all the patients, but these low values were not observed in the patients from the comrol group (P > 0.001). The reasons for hypocholesterolaemia were haemodilution during the earliest 24 hours after trauma, low rafe of cholesterol and its precursors synthesis and the consumption of serum cholesterol in an unknown proces. Average time for which hypocholesterolaemia lasted was 9±3.2 days.

Keywords: hypocholesterolaemia; polytrauma; squalene; lathosterol; lanostero

Published: February 1, 2002  Show citation

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Bakalář B, Zadák Z, Pachl J, Hyšpler R, Pažout J. Changes in Cholesterol Metabolism within a Few Days tlfter Severe Trauma. Anest. intenziv. Med. 2002;13(1):10-11.
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