Anest. intenziv. Med. 2001;12(2):73-80

Pathophysiology of Gut Failure in MODSArticles

I. Chytra, E. Kasal, R. Pradl, A. Židková, P. Altman
Anesteziologicko-resuscitační klinika, Fakultní nemocnice, Plzeň, přednosta doc. MUDr. Eduard Kasal, CSc.

This review article discusses pathophysiology of gut failure and its relation to multi-organ failure (MOF). Triggering factors are reviewed withpathophysiologic mechanisms which take part on the increase of intestinal wall permeability, leading to translocation of bacteria or their toxins fromthe intestinal lumen. In conclusion, the authors state that in spite of deemed connection between bacterial translocation, increased intestinal wallpermeability and the development of MOSF, there is no clear definition or evidence of that relationship.

Keywords: bacterial translocation; intestinal wall permeability

Published: April 1, 2001  Show citation

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Chytra I, Kasal E, Pradl R, Židková A, Altman P. Pathophysiology of Gut Failure in MODS. Anest. intenziv. Med. 2001;12(2):73-80.
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