Anest. intenziv. Med. 2001;12(1):47-48

Lethal Intoxication with AmphetaminesArticles

P. Nohel, R. Kraus
Anesteziologicko-resuscitaè
ní klinika Fakultní nemocnice u sv. Anny v Brně, přednosta doc. MUDr. Pavel Ševčík, CSc.

Drug abuse becomes more common than ever before. Pervitin (methamphetamine) and other stimulants belong to the most abused "hard" drugsin our country. Severe intoxication with amphetamine derivates may present as hyperpyrexia, rhabdomyolysis, acute renal insufficiency, coagulopathyand multiorgan failure. Dantrolene administration in those cases is discussed. Considering the pros and cons, early administration is probably advisableas a part of maximally intensive care for a young intoxicated patient. Early administration of antithrombin III should be a part of the DIC treatmentprotocol.

Keywords: intoxication; amphetamines; hyperthermia; dantrolene

Published: February 1, 2001  Show citation

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Nohel P, Kraus R. Lethal Intoxication with Amphetamines. Anest. intenziv. Med. 2001;12(1):47-48.
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