Beta-blokátory v intenzivní a urgentní medicíně: update 2025 

prof. MUDr. Vladimír Černý, Ph.D., FCCM, FESAIC, doc. MUDr. Roman Škulec, Ph.D.

Anest. intenziv. Med. 2025;36(Suppl.A)

Year 2024 in review – the journal Anesteziologie a intenzivní medicínaEditorial

David Astapenko, Jan Beneš, Vladimír Černý, Martina Kosinová, Jiří Málek

Anest. intenziv. Med. 2025;36(5):325 | DOI: 10.36290/aim.2025.069

Year 2025 in review - Acute pain managementReview Article

Málek J.

Anest. intenziv. Med. 2025;36(5):388-393 | DOI: 10.36290/aim.2025.067

This article presents a selected review of articles and topics published in the field of acute pain management over the past approximately 14 months. It focuses on new developments in systemic analgesia, pain management procedures, and selected international guidelines.

Year 2025 in review - Regional aneasthesiaReview Article

Nalos D., Beňo L., Matrasová Z.

Anest. intenziv. Med. 2025;36(5):384-387 | DOI: 10.36290/aim.2025.064

The review article offers the most interesting information from the available literature on regional anesthesia useful for daily practice. In addition to new information and clarification of procedures and indications in ultrasound-guided peripheral blocks, it brings news from a recent recommendation on the approach to patients on anticoagulant therapy.

Year 2025 in review - Acute respiratory failure and lung supportReview Article

Máca J., Burša F., Sklienka P.

Anest. intenziv. Med. 2025;36(5):377-383 | DOI: 10.36290/aim.2025.066

Several original papers on the topic of acute respiratory failure (ARF) were published in 2025, including studies that support respiratory functions through mechanical ventilation (MV) or the veno-venous form of extracorporeal membrane oxygenation (VV ECMO). The aim of this text is to introduce readers to selected works that, according to the authors, may be of interest not only to researchers in the field but also to physicians in clinical practice. The review article is divided into several sections; the first includes randomized papers and post-hoc analysis of papers already published. The second part is devoted to large prospective observational...

A year 2025 in review - Anaesthesiology in obstetricsReview Article

Štourač P., Bláha J., Harazim H., Mannová J., Nosková P., Kosinová M., Pešková K., Seidlová D.

Anest. intenziv. Med. 2025;36(5):371-376 | DOI: 10.36290/aim.2025.062

The article highlights and discusses several current topics that have been published in the field of anaesthesiology in obstetrics in the Czech Republic and abroad last year. It summarizes new challenges in the field of obstetric anesthesia, including the use of AI and simulations in this area. It also presents new developments in systemic and neuroaxial obstetric analgesia, caesarean section anaesthesia, and emergencies in the peripartum period.

Year 2025 in review - Paediatric anaesthesia and intensive careReview Article

Klabusayová E., Harazim H., Štourač P.

Anest. intenziv. Med. 2025;36(5):368-370 | DOI: 10.36290/aim.2025.061

The article offers an overview of the most impactful publications of the past year. It highlights key findings and emerging trends with direct relevance to the anaesthesiology practice and care of critically ill children, helping readers quickly navigate the latest developments in the field. The selected studies are of high scientific quality, and their results can be directly applied in clinical practice. This article thus serves as a practical guide for physicians and healthcare professionals working in pediatric anaesthesiology and intensive care.

Year 2025 in review - General anaesthesiaReview Article

Bláha J., Nguyenová Q. G., Kapráľová K., Bartošová T.

Anest. intenziv. Med. 2025;36(5):360-367 | DOI: 10.36290/aim.2025.063

This article provides an incomplete overview of randomised studies, systematic reviews, and meta-analyses published in the last 12 months in the area of general anaesthesia. The most frequently mentioned topics, and therefore those selected by the authors, are opioid-free and opioid-sparing anaesthesia, new approaches to airway management, remimazolam as a stable and reversible hypnotic, multimodal PONV prophylaxis, personalised monitoring of anaesthesia depth, and artificial intelligence models in anaesthesiology. Overall, the text focuses on the shift towards safer, individualised, and data-driven anaesthesia.

Year 2025 in review - Chronic pain therapyReview Article

Fricová J.

Anest. intenziv. Med. 2025;36(5):357-359 | DOI: 10.36290/aim.2025.068

Year 2025 introduces major advancements in neurobiological concepts of chronic pain, particularly through the identification of dopaminergic modulation as a novel therapeutic framework. This article summarises key developments in international initiatives, pharmacotherapy, non‑pharmacological interventions, clinical guidelines and neurobiological mechanisms of pain. It follows the structure and style of the 2024 overview and highlights how new insights are shaping current and future pain management.

Year 2025 in review - Emergency medicine in the emergency departmentsReview Article

Škulec R.

Anest. intenziv. Med. 2025;36(5):351-356 | DOI: 10.36290/aim.2025.060

In this article, the author presents a set of annotated papers published in 2025 in the world literature that are significantly related to emergency medicine. Publications from the pre-hospital setting are not included in the selection.

Year 2025 in review - Pre­‑hospital emergency medicineReview Article

Škulec R.

Anest. intenziv. Med. 2025;36(5):346-350 | DOI: 10.36290/aim.2025.059

In this article, the author presents a set of annotated papers published in 2025 in the world literature that are significantly related to pre-hospital emergency medicine. Publications from the emergency departments are not included in the selection.

Year 2025 in review - SepsisReview Article

Karvunidis T., Královcová M.

Anest. intenziv. Med. 2025;36(5):342-345 | DOI: 10.36290/aim.2025.065

This year's overview offers an objective and critical discussion as well as the authors' subjective perspective and commentary on selected publications in the field of sepsis, particularly regarding their relevance to everyday bedside clinical practice. The studies discussed include the REMAP-CAP Corticosteroid Domain RCT, SCREEN, ADAPT-Sepsis, and HELLO trials.

Year 2025 in review - Cardiac anaesthesia and postoperative careReview Article

Michálek P., Říha H., Šoltés J., Kunstýř J.

Anest. intenziv. Med. 2025;36(5):336-341 | DOI: 10.36290/aim.2025.057

This article summarizes newly published findings in the field of anesthesia and perioperative care for procedures on the heart and thoracic aorta. Special attention is paid to new global and European guidelines for procedures using cardiopulmonary bypass in adults and for open heart valve surgeries. Furthermore, advances in the use of regional anesthesia techniques of the chest wall for perioperative and postoperative pain management are discussed, including the use of ultrasound navigation and a description of the effectiveness of continuous techniques. As is customary, new findings in the issues of heart transplantation and postoperative care in...

Year 2025 in review - Cardiovascular issues in intensive care and perioperative medicineReview Article

Pořízka M., Šoltés J., Pudil J., Horejsek J.

Anest. intenziv. Med. 2025;36(5):328-335 | DOI: 10.36290/aim.2025.058

Year 2025 brought significant advances in the field of cardiovascular issues in intensive and perioperative medicine. Research has focused primarily on the individualization of circulatory support, optimization of perfusion targets, and more accurate risk assessment. In the treatment of circulatory shock, there is a prevailing trend toward physiologically oriented, personalized strategies emphasizing hemodynamic phenotypes and a balance between fluid therapy, vasopressors, and mechanical circulatory support. Evidence continues to grow for the selective use of advanced methods, including mechanical cardiac support and extracorporeal cardiopulmonary...

Highlights from literatureHighlights from the literature

Horáček M., Klučka J., Skříšovská T.

Anest. intenziv. Med. 2025;36(4):314-321

Abstrakty posterů z kongresu ČSARIM 2025Congress abstracts

Redakce

Anest. intenziv. Med. 2025;36(4):302-313

Ocenění ČSARIM 2025Reports from professional societies

Redakce

Anest. intenziv. Med. 2025;36(4):298-301

Česká anesteziologická cesta 2025Editorial

Horáček M., Beneš J.

Anest. intenziv. Med. 2025;36(4):237-238 | DOI: 10.36290/aim.2025.056

Letter to the Editor: Transient BIS elevations during caloric testing in brain death: artifactual or physiological?Correspondence

Ceylan Delice M., Kavrut Ozturk N.

Anest. intenziv. Med. 2025;36(4):296-297 | DOI: 10.36290/aim.2025.049

Translumbar access to the inferior vena cava - rescue option for insertion of a central venous catheterShort Communication

Michálek P., Brožek T., Kaván J., Forejtová L., Novák M., Malík J.

Anest. intenziv. Med. 2025;36(4):292-295 | DOI: 10.36290/aim.2025.054

Long-term central venous access is currently indicated mainly in patients receiving parenteral nutrition, dialysis, or chemothera­py. Some patients require the catheter to be inserted repeatedly or for a period longer than one year. A translumbar approach with direct insertion of a central venous catheter into the inferior vena cava can be an alternative in cases of confirmed superior vena cava obstruction or significant stenosis. This technique is relatively difficult; it requires fluoroscopy or computed tomography guidance and cooperation of an interventional radiologist. This review article describes indications, technique of insertion, and complications...

Patient with progressive pulmonary tuberculosis on ECMOCase Report

Mica P., Rychlíčková J., Čundrle I., Pokorná A.

Anest. intenziv. Med. 2025;36(4):287-291 | DOI: 10.36290/aim.2025.046

Miliary pulmonary tuberculosis is a rare but severe form of disseminated disease that can lead to acute respiratory distress and multiorgan failure. We present the case of a 46-year-old man whose tuberculosis manifested as severe respiratory failure requiring artificial pulmonary ventilation and subsequent use of extracorporeal membrane oxygenation. The case highlights the diagnostic difficulty, complexity of care and therapeutic challenges with emphasis on individualized pharmacotherapy in an interdisciplinary collaboration.

Risk­‑assesment before lung surgery - what's new? Narrative review articleReview Article

Bartoš Š., Predáč A., Čundrle I.

Anest. intenziv. Med. 2025;36(4):280-286 | DOI: 10.36290/aim.2025.041

Surgical treatment is the primary therapeutic option for patients with early-stage lung cancer. The most common causes of perioperative morbidity and mortality in these patients are postoperative pulmonary complications. Peak oxygen consumption (VO2) has long been considered the gold standard for predicting these complications. In recent years, several new parameters for risk assessment have been described in peer-reviewed journals, notably ventilatory efficiency (VE/VCO2 slope) and end-tidal CO2. Both parameters have demonstrated excellent predictive ability for postoperative pulmonary complications, even in patients in whom peak VO2 failed. This...

The specifics of psychiatric patients in the context of anaesthesiaReview Article

Apjarová T., Bönischová T., Kosinová M., Štourač P.

Anest. intenziv. Med. 2025;36(4):272-279 | DOI: 10.36290/aim.2025.045

The prevalence of psychiatric disorders is rising globally, with one in five individuals now affected. As a result, patients taking psychotropic medications are encountered frequently in clinical practice. This article explores the specific considerations in providing anaesthetic care to psychiatric patients, with a focus on pharmacological interactions between psychotropic and anaesthetic drugs, as well as on the risks associated with their combined use. Additionally, the article discusses strategies to minimize potential complications during the perioperative period.

Current methods of cardiac output monitoringReview Article

Klimovič A., Smékalová O., Kletečka J., Beneš J., Zatloukal J.

Anest. intenziv. Med. 2025;36(4):262-271 | DOI: 10.36290/aim.2025.048

Cardiac output monitoring and other parameters as part of extended hemodynamic monitoring represent an advanced tool for the early detection of circulatory disturbances that cannot be identified through standard vital sign monitoring. Such disturbances may lead to inadequate tissue oxygen delivery and subsequent clinical deterioration. Extended hemodynamic monitoring is indicated in patients who do not respond to initial therapy, and in the perioperative setting, it is recommended for high-risk patients undergoing high-risk surgical procedures. The choice of cardiac output monitoring modality may be challenging due to the wide range of available technologies,...

Hypertonic sodium lactate solution in the resuscitation of septic shock: a narrative review of pathophysiology, preclinical and clinical dataReview Article

Kříž M., Nalos M., Vintrych P., Müller J., Raděj J., Matějovič M.

Anest. intenziv. Med. 2025;36(4):253-261 | DOI: 10.36290/aim.2025.047

Aim: Excessive fluid accumulation during fluid resuscitation is associated with increased mortality and organ dysfunction. The promise of personalized fluid therapy lies in maximizing its benefits while minimizing the harmful effects of fluid resuscitation. This includes prediction of the hemodynamic response to infusion and careful consideration of its volume and composition in the context of the clinical situation. In light of recent paradigm shifts in lactate metabolism, we therefore discuss current evidence on the concept of low-volume intravenous resuscitation with hypertonic sodium lactate (HSL). Design: A narrative review of the current literature...

Comparison of ibuprofen and paracetamol combination with ketorolac and paracetamol in patients undergoing gynecologic surgery:  A review of pain level, coagulation profile, and interleukin-6 levelsOriginal Article

Maarif M. K., Musba A. M. T., Datu M. D., Gaus S., Wirawan N. S., Adil A.

Anest. intenziv. Med. 2025;36(4):247-252 | DOI: 10.36290/aim.2025.043

Background: Postoperative pain management in gynecological surgery remains a significant challenge, with many patients experiencing moderate to severe pain despite standard analgesic interventions. The risk of complications, such as bleeding and prolonged recovery, is heightened by the use of certain analgesics, emphasizing the need for optimal pain management strategies. This study compares the efficacy of two multimodal analgesic regimens-ibuprofen-paracetamol and ketorolac-paracetamol-on pain, coagulation, and interleukin-6 (IL-6) levels.  Methods: A double-blind randomized trial was conducted with 40 patients undergoing gynecological surgery....

Experiences of HCPs working at ICUs with a virtual reality in postgraduate training - multicentre surveyOriginal Article

Prokopová T., Diabelko D., Vafková T., Klabusayová E., Hudec J., Štourač P.

Anest. intenziv. Med. 2025;36(4):241-246 | DOI: 10.36290/aim.2025.039

Objective: The primary goal of this study was to explore the experience of health care professionals (HCPs) working at intensive care units (ICUs) with virtual reality (VR) involvement in postgraduate training. The second goal was to explore the expectations and common concerns associated with the VR-based courses. Design: Observational online cross-sectional survey. Setting: ICUs of various types across hospitals in the Czech Republic. Material and methods: An online questionnaire for HCPs working at ICUs. Methods of descriptive statistics were used for data interpretation. Results: A total...

Zajímavosti z literaturyHighlights from the literature

Horáček M., Klučka J., Skříšovská T.

Anest. intenziv. Med. 2025;36(3):226-233

How strongly should clinicians adhere to guidelines?Editorial

Černý V.

Anest. intenziv. Med. 2025;36(3):155 | DOI: 10.36290/aim.2025.044

Diagnostika a léčba život ohrožujícího krvácení u dětských pacientů v intenzivní a perioperační péči 2024New guidelines

Zaoral T., Blatný J., Jonáš J., Lauková K., Nosáľ S., Raffaj D., Kratochvíl M., Slívová I., Černý V.

Anest. intenziv. Med. 2025;36(3):217-225 | DOI: 10.36290/aim.2025.035