Anest. intenziv. Med. 2023;34(5):239-243 | DOI: 10.36290/aim.2023.067
Year 2023 in review - Chronic pain treatmentReview Article
- Klinika anesteziologie, resuscitace a intenzivní medicíny,
- Centrum pro léčbu bolesti 1. lékařské fakulty Univerzity Karlovy a Všeobecné fakultní nemocnice, Praha
The article presents a selection of interesting basic research, particularly the importance of microglia in chronic pain, new recommendations to optimize and accelerate the development of "precision" treatments for chronic pain, IASP recommendations for the year of integrative medicine, which was 2023. Also of note is alcohol-induced mechanical allodynia, where chronic alcohol consumption can make people more sensitive to pain through two different molecular mechanisms. A final no less interesting topic is the introduction of nasal naloxone to the ame-ric market as an over-the-counter drug. Only international and relevant sources are discussed.
Keywords: chronic pain, microglia, astrocytes, epigenetics, IMMPACT recommendations, IASP, alcohol‑induced mechanical allodynia, FDA, naloxone spray.
Received: December 6, 2023; Accepted: December 6, 2023; Prepublished online: December 11, 2023; Published: December 20, 2023 Show citation
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