Anest. intenziv. Med. 1999;10(6):268-272

Cytokine balance and its modulation in patients undergoing cardiopulmonarybypass surgeryArticles

S. Kleinschmidt
Klinik für Anaesthesiologie und Intensivmedizin der Universitätskliniken des Saarlandes, Homburg/Saar

An adequate balance of homeostasis, represented by various pro- and anti-inflammatory cytokines, is important for the maintenance of health.Deviation of the normal balance of pro- and anti-inflammatory cytokines will lead to severe restrictions of immune response. Cardiopulmonary bypass(CPB) is regarded as a reproducible model of inflammatory response and constitutes a major challenge to the patient's ability to maintain this balance.Recent research has focused on the pro- and inflammatory cytokine balance, immune-modulating therapies and techniques to characterize the patient'sindividual immune status. The importance of cytokine balance and the various states of inflammatory response are briefly described and discussed.

Keywords: cardiopulmonary bypass; cytokines; modulation of immune status

Published: December 1, 1999  Show citation

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Kleinschmidt S. Cytokine balance and its modulation in patients undergoing cardiopulmonarybypass surgery. Anest. intenziv. Med. 1999;10(6):268-272.
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