Anesteziologie a intenzivní medicína, 2006 (vol. 17), issue 1
Antifibrinolytic agents in off-pump cardiac surgery: analysis of blood loss, safety and cost-effectivenessAnaesthesiology - Original Paper
T. Vaněk, M. Jareš, R. Fajt, Z. Straka, M. Malý
Anest. intenziv. Med. 2006;17(1):6-13 
Objective:To compare the haemostatic effects of fibrinolytic inhibitors (tranexamic acid, aprotinin) vs. placebo in off-pump coronary artery bypass surgery and to evaluate the impact of this therapy on cost-effectiveness. Design:Prospective, randomized, double-blind study. Setting:University Teaching Hospital, Prague, Czech Republic. Material and Method:100 patients were enrolled in the study and 91 of them were assessed (group A, n = 32, tranexamic acid 1 g before skin incision followed by continuous infusion at 200 mg/h; group B, n = 29, aprotinin 1,000,000 IU before skin incision and 250,000...
Oxygen transfer and pulmonary hypertension as predictors of early mortality in lung transplant patientsAnaesthesiology - Original Paper
D. Romportl, Z. Havelka, A. Hodek, M. Pelichovská, I. David, R. Lischke, J. Šimonek, K. Cvachovec, P. Pafko, M. Hladíková
Anest. intenziv. Med. 2006;17(1):14-20
Objective:To identify measurable predictors of survival in patients after lung transplantation. Design:Retrospective monocentric clinical study. Setting:Department of Anaesthesiology and Resuscitation of the 2nd Medical School and the Institute for Postgraduate Medical Education, Charles University Prague-Motol. Material and Methods:47 patients after single and double lung transplants were included. PaO₂, mean pulmonary artery pressure and hypoxemic index were selected as the possible survival predictors. The assessed data were collected preoperatively and 2, 24 and 48 hours postoperatively,...
Vascular anaesthesia at the beginning of the third milleniumAnaesthesiology - Comprehensive Report
P. Michálek, M. Stern, V. Kubricht, J. Šoupal
Anest. intenziv. Med. 2006;17(1):21-29
Anaesthesia for vascular surgery has been developing rapidly in the last decade, simultaneously with surgery. The anaesthetist must master a broad spectre of manual skills and theoretical knowledge. Pulmonary artery catheters and/or transoesophageal echocardiography are frequently used in aortic surgery to monitor the haemodynamics. Another option is to estimate cardiac output by analysis of the arterial pressure curve. Monitoring of the neurological function of the brain and spinal cord is necessary in carotid surgery and descending aortic procedures. Haemocoagulation disorders are monitored using thrombelastography and Sonoclot. In this article the...
The cardiovascular system in the elderly and perioperative riskAnaesthesiology - Comprehensive Report
P. Janský
Anest. intenziv. Med. 2006;17(1):30-33
Life expectancy for men and women has increased and the proportion of elderly population is rising steadily. Concomitantly, the prevalence of cardiovascular disease has increased with aging and represents a leading cause of morbidity and mortality in older persons. The clinical manifestation and significance of various heart and vascular pathologies frequently differs from the younger age groups. Both cardiovascular disease and age-associated morphological and physiological changes of the cardiovascular system may significantly influence all aspects of perioperative evaluation and care in the elderly. The main challenge in preoperative evaluation is...
The prospective study on the effect of a preemptive long-term postoperative administration of a low-dose ketamine on the incidence of chronic post-mastectomy painAlgeziology
J. Málek, A. Kurzová, M. Bendová, P. Nosková, M. Strunová, T. Vedral
Anest. intenziv. Med. 2006;17(1):34-37
Objective:The N-methyl D-aspartate receptor is involved both in the postoperative central sensitization and the development of chronic postoperative pain. Its antagonist ketamine is used for the enhancement of postoperative analgesia and treatment of chronic pain. There is little information concerning the long-term effect of perioperative administration of ketamine on chronic pain. We have designed a study to test the hypothesis that pre-emptive and long-term postoperative administration of low-dose ketamine lowers the incidence of chronic postoperative pain. Design:Prospective, blind clinical trial. Setting:Dept....
Current methods of mechanical circulatory supportIntensive Care Medicine - Comprehensive Report
A. Březina, H. Říha, J. Mašín
Anest. intenziv. Med. 2006;17(1):38-44
Mechanical circulatory support is a system designed to help the failing heart in the case of pharmacological support failure and if cardiac surgery is not possible option. The article is devided into four parts. It starts with a short historical overview of mechanical circulatory support development, followed by indications for use with physiological implications. At the end there is a review of the most important devices used today.
The controversial role of ventilation during cardiopulmonary resuscitationIntensive Care Medicine - Comprehensive Report
J. Málek, M. Pokorná
Anest. intenziv. Med. 2006;17(1):45-48
The article presents new evidence regarding cardiopulmonary resuscitation.