Anest. intenziv. Med. 2019;30(2):86-89 | DOI: 10.36290/aim.2019.027

Mucormycosis in solid organ transplant recipientsIntesive Care Medicine - Case Report

S. Palásková*, E. Kieslichová
Klinika anesteziologie, resuscitace a intenzivní péče, Transplantcentrum, Institut klinické a experimentální medicíny

Mucormycosis is a very serious, invasive fungal infection, occurring frequently in patients with a modified immune response. Mortality in cases of a generalized form of mucormycosis can reach 96 %. The principles of successful treatment of this disease are early diagnosis and aggressive antimycotic and/or surgical therapy. In this case report we point out the clinical importance of correct timing of therapy, even though even early and appropriate management does not always guarantee survival.

Keywords: mucormycosis; solid organ transplantation; antimycotic therapy

Received: September 10, 2019; Accepted: April 19, 2019; Published: April 1, 2019  Show citation

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Palásková S, Kieslichová E. Mucormycosis in solid organ transplant recipients. Anest. intenziv. Med. 2019;30(2):86-89. doi: 10.36290/aim.2019.027.
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    References

    1. Gavalda J, Meije Y, Fortún J, et al. Invasive fungal infections in solid organ transplant recipients. Clin Microbiol Infect. 2014;20:27-48. Go to original source... Go to PubMed...
    2. Petrikkos G, Skiada A, Lortholary O, et al. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis. 2012;54:23-34. Go to original source... Go to PubMed...
    3. Neofytos D, Fishman JA, Horn D, et al. Epidemiology and outcome of invasive fungal infections in solid organ transplant recipients. Transpl Infect Dis. 2010;12:220-229. Go to original source... Go to PubMed...
    4. Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment. Clin Microbiol Infect. 2004;10:31-47. Go to original source... Go to PubMed...
    5. Lemonovich TL. Mold infections in solid organ transplant recipients. Infect Dis Clin North Am. 2018;32:687-701. Go to original source... Go to PubMed...
    6. Skiada A, Lass-Floerl C, Klimko N, et al. Challenges in the diagnosis and treatment of mucormycosis. Med Mycol. 2018;56:93-101. Go to original source... Go to PubMed...
    7. Hammond PS, Bialek R, Milner DA, et al. Molecular methods to improve diagnosis and identification of mucormycosis. J Clin Microbiol. 2011;49:2151-2153. Go to original source... Go to PubMed...
    8. Bialek R, Zelck UE. PCR-diagnostik von mukormykosen aus gewebeschnitten. Der Pathologe. 2013;34:511-518. Go to original source... Go to PubMed...
    9. Liu M, Bruni GO, Taylor CM, et al. Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar. Sci Rep. 2018;8:5243. Go to original source... Go to PubMed...
    10. Machouart M, Larché J, Burton K, et al. Genetic identification of the main opportunistic mucorales by PCR-restriction fragment length polymorphism. J Clin Microbiol. 2006;44:805-810. Go to original source... Go to PubMed...

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