Anest. intenziv. Med. 2007;18(2):73-84
The use of neuromuscular blockade in the departments of anaesthesia in the Czech Republic in 2006 - a questionnaire surveyAnaesthesiology - Original Paper
- 1 Klinika anesteziologie a resuscitace, Fakultní nemocnice a Lékařská fakulta Univerzity Palackého, Olomouc
- 2 Klinika anestéziológie a intenzívnej medicíny, Fakultná NsP Jána Adama Reimana, Prešovská univerzita a Slovenská zdravotnícka univerzita, Prešov, Slovenská republika
Objective:
To evaluate the use of muscle relaxants in the anaesthetic departments in the Czech Republic.
Design:
Prospective, multicentre, questionnaire, correspondence study.
Settings:
Anaesthetic departments, Czech Republic.
Material and methods:
We posted a structured questionnaire regarding the use and choice of muscle relaxants depending on the length of surgery to the heads of 140 Czech departments of anaesthesia.We were also interested in the methods and techniques of neuromuscular blockade monitoring and the dose regimens for block reversal by neostigmine. Descriptive statistics were used to analyze the results.
Results:
96% of the questionnaires returned. Nine neuromuscular blockers are currently available in the Czech Republic (suxamethonium, alcuronium, atracurium, cisatracurium, mivacurium, pancuronium, pipecuronium, rocuronium and vecuronium). Atracurium (74%), cisatracurium (41%) and vecuronium (20%) are the most preferred ones. Suxamethonium is most commonly used for patients at risk of aspiration (91%) and those with potential difficult airways (75%). A bolus dose with or without top-ups is the most frequent strategy of administration.Timing (63%) is the most commonly used special procedure followed by priming (31%) and precurarization (22%). Monitoring of neuromuscular blockade relies mainly on clinical judgement (73%), as 50% of departments do not have the monitoring equipment. This is based on expert (40%), economical (42%) and technical (25%) reasons. Neostigmine is usually administered according to clinical signs (90%). The most frequently used dose is 1.0 mg.
Conclusion:
The same muscle relaxants are used in the Czech Republic as worldwide. An initial bolus and top-ups is the most frequently used strategy for muscle relaxation. There is a noteworthy lack of monitoring facilities in Czech anaesthetic departments. A relatively small dose of neostigmine is used for reversal.
Keywords: neuromuscular blockade; neuromuscular blocker; neostigmine; monitoring; questionnaire survey
Published: April 1, 2007 Show citation
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References
- Adamus, M. Svalová relaxace v anesteziologii - mýty a realita. X. kongres České společnosti anesteziologie, resuscitace a intenzivní medicíny ČLS JEP, Luhačovice, 25.-27. 9. 2003. In Sborník vyžádaných přednášek, 1. vydání, s. 18-22. ISBN 80-239-1306-9.
- Foldes, F. F. The impact of neuromuscular blocking agents on the development of anaesthesia and surgery. In Monographs in anaesthesiology (ed. Agoston, S., Bowman, W. C.), Amsterdam : Elsevier, 19, p. 1-17.
- Evers, A. S, Maze, M. Anesthetic Pharmacology. Physiological Principles and Clinical Practice: A Companion to Miller's Anesthesia. 1. vydání, Philadelphia, Pennsylvania : Elsevier, 2004, 1000 p., ISBN 0-443-06579-9.
- Herold, I. Svalová relaxancia v anesteziologii a intenzivní péči. 1. vydání. Praha : Maxdorf, 2004, 268 s., ISBN 80-7345-025-9.
- Viby-Mogensen, J. Postoperative residual curarization and evidence-based anaesthesia. Br. J. Anaesth., 2000, 84, p. 301-303.
Go to original source...
Go to PubMed...
- Adamus, M., Marek, O. Monitorování účinku kurarimimetik během anestezie - současný stav v České republice. Anest. neodkl. Péče, 2000, 11, s. 245-250.
- Adamus, M., Bělohlávek, R., Vujčíková, M., Janásková, E. Vliv odlišných dávek rocuronia na jeho farmakodynamický profil: prospektivní studie. Anest. intenziv. Med., 2004, 15, s. 269-275.
- Sparr, H. J., Johr, M. Succinylcholine - update. Anaesthesist, 2002, 51, p. 565-575.
Go to original source...
Go to PubMed...
- Osmer, C., Vogele, C., Zickmann, B., Hempelmann, G. Comparative use of muscle relaxants and their reversal in three European countries: a survey in France, Germany and Great Britain. Eur. J. Anaesthesiol., 1996, 13, p. 389-399.
Go to original source...
Go to PubMed...
- Glass, P. S. A., Wilson, W., Mace, J. A., Wagoner, R. Is the priming principle both effective and safe? Anesth. Analg., 1989, 68, p. 127-134.
Go to original source...
Go to PubMed...
- Jones, R. M. The priming principle: how does it work and should we be using it? Br. J. Anaesth., 1989, 63, p. 1-3.
Go to original source...
Go to PubMed...
- Sparr, H. J. Choice of the muscle relaxant for rapid-sequence induction. Eur. J. Anaesthesiol., Suppl., 2001, 23, p. 71-76.
Go to original source...
- Mak, P. H., Irwin, M. G. The effect of cisatracurium and rocuronium on cisatracurium precurarization and the priming principle. J. Clin. Anesth., 2004, 16, p. 83-87.
Go to original source...
Go to PubMed...
- Spence, D., Domen-Herbert, R., Boulette, E., Olson, R. L., Vacchiano, C., Maye, J. A comparison of rocuronium and lidocaine for the prevention of postoperative myalgia after succinylcholine administration. AANA J., 2002, 70, p. 367-372.
Go to PubMed...
- Martin, R., Carrier, J., Pirlet, M., Claprood, Y., Tetrault, J. P. Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia. Can. J. Anaesth., 1998, 45, p. 521-525.
Go to original source...
Go to PubMed...
- Motamed, C., Choquette, R., Donati, F. Rocuronium prevents succinylcholine-induced fasciculations. Can. J. Anaesth., 1997, 44, p. 1262-1268.
Go to original source...
Go to PubMed...
- Tsui, B. C., Reid, S., Gupta, S., Kearney, R., Mayson, T., Finucane, B. A rapid precurarization technique using rocuronium. Can. J. Anaesth., 1998, 45, p. 397-401.
Go to original source...
Go to PubMed...
- Hernandez-Palazon, J., Noguera-Velasco, J., Falcon-Arana, L. F., Domenech-Asensi, P., Burguillos-Lopez, S., Nuno de la Rosa-Carrillo, V. Precurarization with rocuronium prevents fasciculations and biochemical changes after succinylcholine administration. Rev. Esp. Anestesiol. Reanim., 2004, 51, p. 184-189.
- Kim, J. H., Cho, H., Lee, H. W., Lim, H. J., Chang, S. H., Yoon, S. M. Comparison of rocuronium and vecuronium pretreatment for prevention of fasciculations, myalgia and biochemical changes following succinylcholine administration. Acta Anaesthesiol. Sin., 1999, 37, p. 173-178.
Go to PubMed...
- Sieber, T. J., Zbinden, A. M., Curatolo, M., Shorten, G. D. Tracheal intubation with rocuronium using the "timing principle". Anesth. Analg., 1998, 86, p. 1137-1140.
Go to original source...
- Geldner, G., Fuchs-Buder, T., Hofmockel, R., Diefenbach, C., Ulm, K., Blobner, M. The use of muscle relaxants for routine induction of anesthesia in Germany. Anaesthesist, 2003, 52, p. 435-441.
Go to original source...
Go to PubMed...
- Viby-Mogensen, J., Jensen, E., Werner, M., Kirkegaard Nielsen, H. Measurement of acceleration: a new method of monitoring neuromuscular function. Acta Anaesthesiol. Scand., 1988, 32, p. 45-48.
Go to original source...
Go to PubMed...
- Sorgenfrei, I. F., Viby-Mogensen, J., Swiatek, F. A. Does evidence lead to a change in clinical practice? Danish anaesthetists' and nurse anesthetists' clinical practice and knowledge of postoperative residual curarization. Ugeskrift for laeger, 2005, 167, p. 3878-3882.
Go to PubMed...
- Baillard, C., Gehan, G., Reboul-Marty, J., Larmignat, P., Samama, C. M., Cupa, M. Residual curarization in the recovery room after vecuronium. Br. J. Anaesth., 2000, 84, p. 394-395.
Go to original source...
Go to PubMed...
- McCaul, C., Tobin, E., Boylan, J. F., McShane, A. J. Atracurium is associated with postoperative residual curarization. Br. J. Anaesth., 2002, 89, p. 766-769.
Go to original source...
Go to PubMed...
- Greer, R., Harper, N. J., Pearson, A. J. Neuromuscular monitoring by intensive care nurses: comparison of acceleromyography and tactile assessment. Br. J. Anaesth., 1998, 80, p. 384-385.
Go to original source...
Go to PubMed...
- Mortensen, C. R., Berg, H., El-Mahdy, A., Viby-Mogensen, J. Perioperative monitoring of neuromuscular transmission using acceleromyography prevents residual neuromuscular block following pancuronium. Acta Anaesthesiol. Scand., 1995, 39, p. 797-801.
Go to original source...
Go to PubMed...
- Bevan, D. Reversal of neuromuscular block: the case FOR reversal. Acta Anaesthesiol. Scand., Suppl, 1997, 41, p. 102.
Go to original source...
Go to PubMed...
- Hovorka, J., Korttila, K., Nelskyla, K., Soikkeli, A., Sarvela, J., Paatero, H., Halonen, P., Yli-Hankala, A. Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. Anesth. Analg., 1997, 85, p. 1359-1361.
Go to original source...
- Cheng, C. R., Sessler, D. I., Apfel, C. C. Does neostigmine administration produce a clinically important increase in postoperative nausea and vomiting? Anesth. Analg., 2005, 101, p. 1349-1351.
Go to original source...
Go to PubMed...