Anesteziologie a intenzivní medicína, 2005 (vol. 16), issue 3
Pre-emptive Analgesia with Ketamine and Morphine: a Clinical StudyAnaesthesiology - Original Paper
J. Málek, A. Kurzová, I. Kraus
Anest. intenziv. Med. 2005;16(3):138-142 
Objective:To assess if a pre-emptive combination of morphine and ketamine is more effective than if one drug is administered before surgery and the second one after a surgical stimulation. Design:Prospective single-blinded randomized clinical study. Setting:Charles University, Prague, 3rd Medical Faculty, Dept. of Anaesthesiology and Intensive Care. Material and Method:A total of 63 women scheduled for abdominal hysterectomy were randomly divided in three equal groups. Only atropine and diazepam were used for premedication. The group K was administered ketamine 0.6 mg . kg-1 + normal...
Influence of Major Abdominal Surgery on Intra-abdominal Pressure and Perfusion of Splachnic OrgansIntensive Care Medicine - Original Paper
P. Suk, L. Dadák, M. Mašek, Š. Chalupník, J. Žák, P. Štětka, D. Zvoníčková, H. Valouchová, M. Fencl, V. Šrámek
Anest. intenziv. Med. 2005;16(3):143-148
Objective:To assess the incidence of intra-abdominal hypertension and splanchnic hypoperfusion after a major abdominal surgery. Design:Observational, prospective cohort study. Setting:ICU, Surgical Department I, St. Anna's University Hospital, Brno. Material and Methods:Patients undergoing major abdominal surgery were eligible. Intra-abdominal pressure (IAP), gastric tonometry (GT) and arterial blood gases were measured postoperatively at the ICU (T0) and then at T1, T6, T12, T18, T24 . At the same time points abdominal perfusion pressure (APP) and CO2gap were calculated. At T1 and T6, indocyanine...
Selective Decontamination of the Digestive Tract:Why Don't We Apply Evidence in Practice?
H. K. F. Van Saene, L. Silvestri, M. A. De La Cal
Anest. intenziv. Med. 2005;16(3):152-160
Selective decontamination of the digestive tract [SDD] has been assessed in 54 randomised controlled trials (RCTs) and nine meta-analyses of RCTs only.The most recent meta-analysis includes 36 RCTS in 6,922 unselected patients, and shows that SDD, including enteral and parenteral antimicrobials, reduces the odds ratio for pneumonia to 0.35 [0.29 to 0.41], and mortality to 0.78 [0.68 to 0.89]. The absolute mortality reduction was 4.8%. This information implies that 5 ICU-patients need to be treated with SDD to prevent one case of pneumonia, and 21 ICU-patients need to be treated to prevent one death. Two recent large RCTs report an absolute mortality...
Acetaminophene Intoxication: a Case ReportIntesive Care Medicine - Case Report
R. Schmidt, J. Firment, K. Spodník, M. Paľko, P. Jarčuška, E. Veseliny, Ľ. Beňa
Anest. intenziv. Med. 2005;16(3):161-165
The acetaminophene intoxication may be very frequent due to an easy availability of the drug. A serious hepatic impairment may occure after overdose. So far, N-acetylcysteine is the only specific antidote recommended. The authors describe the case of an acetaminophene overdose.