Anest. intenziv. Med. 2025;36(3):194-197 | DOI: 10.36290/aim.2025.030

Donation after circulatory death in a regional hospital in Czech Republic: a case reportCase Report

Kalina M.1-3, Jobánek J.2, 3, Mareš J.2, Pokorná E.4
1 Charles University, Faculty Medicine Hradec Králové, Czech Republic
2 Department of Anaesthesiology, Resuscitation and Intensive Care, Děčín Hospital, Czech Republic
3 Department of Anaesthesiology, Perioperative and Intensive Care Medicine, J. E. Purkinje University in Ústí nad Labem, Masaryk Hospital in Ústí nad Labem, Czech Republic
4 Institute for Clinical and Experimental Medicine, Prague, Czech Republic

Transplantation is a well-established therapeutic option that saves lives and improves the quality of life of patients. A shortage in organs has led to an increased use of donation after circulatory death. Donation after circulatory death is nowadays used in some way in most countries in the developed world. We present two cases of a successfully conducted donation after circulatory death in a regional hospital with the aim to demonstrate the feasibility and share a successful practice.

Keywords: deceased donation, withdrawal of therapy, donation after circulatory death, transplantation, critical care, anaesthesiology

Received: February 20, 2025; Revised: June 13, 2025; Accepted: June 24, 2025; Prepublished online: July 31, 2025; Published: September 30, 2025  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kalina M, Jobánek J, Mareš J, Pokorná E. Donation after circulatory death in a regional hospital in Czech Republic: a case report. Anest. intenziv. Med. 2025;36(3):194-197. doi: 10.36290/aim.2025.030.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Thuong M, Ruiz A, Evrard P, Kuiper M, Boffa C, Akhtar MZ, et al. New classification of donation after circulatory death donors definitions and terminology. Transpl Int. 2016 Jul;29(7):749-59. doi: 10.1111/tri.12776. Epub 2016 May 4. PMID: 26991858. Go to original source... Go to PubMed...
    2. Miñambres E, Rubio JJ, Coll E, Domínguez-Gil B. Donation after circulatory death and its expansion in Spain. Curr Opin Organ Transplant. 2018 Feb;23(1):120-129. doi: 10.1097/MOT.0000000000000480. PMID: 29120882. Go to original source... Go to PubMed...
    3. Manara AR, Murphy PG, O'Callaghan G. Donation after circulatory death. Br J Anaesth. 2012 Jan;108 Suppl 1:i108-21. doi: 10.1093/bja/aer357. PMID: 22194426. Go to original source... Go to PubMed...
    4. Jawitz OK, Devore AD, Patel CB, Keenan JE, Milano CA, Schroder JN. Regional variation in donation after circulatory death heart allograft utilization. JTCVS Open. 2024 Jul 17;21:191-196. doi: 10.1016/j.xjon.2024.07.004. PMID: 39534326; PMCID: PMC11551292. Go to original source... Go to PubMed...
    5. Lomero M, Gardiner D, Coll E, Haase-Kromwijk B, Procaccio F, Immer F, et al; European Committee on Organ Transplantation of the Council of Europe (CD-P-TO). Donation after circulatory death today: an updated overview of the European landscape. Transpl Int. 2020 Jan;33(1):76-88. doi: 10.1111/tri.13506. Epub 2019 Oct 7. PMID: 31482628. Go to original source... Go to PubMed...
    6. Vail EA, Bakhru RN, McGinity AC, Sarge T, Heimbach JK, Tompeck AJ, et al. Best Practices for Intensivists Planning and Opening Hospital-Based Deceased Organ Donor Care Units: Part 1. CHEST Critical Care. 2025 Mar 1;3(1):100110. Go to original source...
    7. Kizer KW, English RA, Hackmann M, editors. Realizing the Promise of Equity in the Organ Transplantation System. Washington, D.C.: National Academies Press; 2022. Go to original source...
    8. https://www.zakonyprolidi.cz/cs/2002-285 [Internet]. 2002 [cited 2025 Jan 29]. Zákon č. 285/2002 Sb. Available from: https://www.zakonyprolidi.cz/cs/2002-285.
    9. Schmidt M, Pokorná E, Duška F. Dárcovství orgánů po nevratné zástavě oběhu: Jak na to? Anest. intenziv. Med. 2020;31(3):114-118. doi: 10.36290/aim.2020.005. Go to original source...
    10. Kompanje EJ, van der Hoven B, Bakker J. Anticipation of distress after discontinuation of mechanical ventilation in the ICU at the end of life. Intensive Care Med. 2008 Sep;34(9):1593-9. doi: 10.1007/s00134-008-1172-y. Epub 2008 May 31. PMID: 18516588; PMCID: PMC2517089. Go to original source... Go to PubMed...
    11. Kramer AH, Holliday K, Keenan S, Isac G, Kutsogiannis DJ, Kneteman NM, et al. Premortem anticoagulation timing and dose in donation after circulatory death: multicentre study of associations with graft function. Can J Surg. 2022 Jul 28;65(4):E474-E484. doi: 10.1503/cjs.023120. PMID: 35902105; PMCID: PMC9343016. Go to original source... Go to PubMed...
    12. Narvaez JRF, Noyes K, Nie J, Kayler LK. Outcomes of DCD kidneys recovered for transplantation with versus without pre-mortem heparin administration. Clin Transplant. 2019 Jul;33(7):e13624. doi: 10.1111/ctr.13624. Epub 2019 Jun 25. PMID: 31162721. Go to original source... Go to PubMed...
    13. Keshava HB, Farver CF, Brown CR, Shafii AE, Murthy SC, Yun JJ, et al. Timing of heparin and thrombus formation in donor lungs after cardiac death. Thorac Cardiovasc Surg. 2013 Apr;61(3):246-50. doi: 10.1055/s-0032-1322627. Epub 2012 Dec 3. PMID: 23208845. Go to original source... Go to PubMed...
    14. Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, et al; Canadian Critical Care Trials Group; Canadian Donation and Transplantation Research Program. Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 Jan 28;384(4):345-352. doi: 10.1056/NEJMoa2022713. PMID: 33503343. Go to original source... Go to PubMed...
    15. Vyhláška č. 115/2013 Sb. [Internet]. 2013 [cited 2025 May 12]. Available from: https://www.zakonyprolidi.cz/cs/2013-115.
    16. Cvachovec K, Černý V, Duška F, Hejna P, Pokorná E, Rusinová K, et al. Doporučený postup před odběrem orgánů od zemřelých dárcůpo nevratné zástavě oběhu. Anest. intenziv. Med. 2014;25(2):145-146.

    Return to the content


    Anesteziologie a intenzivní medicína

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.