Anest. intenziv. Med. 2023;34(5):204-207 | DOI: 10.36290/aim.2023.048

Year 2023 in review – SepsisReview Article

Karvunidis T.
Jednotka intenzivní péče, I. interní klinika, Lékařská fakulta v Plzni, Univerzita Karlova a Fakultní nemocnice Plzeň
Biomedicínské centrum, Lékařská fakulta v Plzni, Univerzita Karlova, Plzeň

This year's summary critically discusses important publications regarding to adjuvant corticosteroid therapy in community-acquired pneumonia, blood-glucose control, supraventricular arrhytmias treatment, and fluid therapy in critically ill septic patiens.

Keywords: sepsis, corticotherapy, glucose control, supraventricular arrytmia, fluid therapy.

Received: October 19, 2023; Accepted: October 19, 2023; Prepublished online: December 6, 2023; Published: December 20, 2023  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Karvunidis T. Year 2023 in review – Sepsis. Anest. intenziv. Med. 2023;34(5):204-207. doi: 10.36290/aim.2023.048.
Download citation

References

  1. Cilloniz C, Ferrer M, Liapikou A, Garcia­‑Vidal C, Gabarrus A, Ceccato A, et al. Acute respiratory distress syndrome in mechanically ventilated patients with community­‑acquired pneumonia. Eur Respir J. 2018 Mar 29;51(3):1702215. doi: 10.1183/13993003.02215-2017. PMID: 29545274. Go to original source... Go to PubMed...
  2. Meijvis SC, Hardeman H, Remmelts HH, Heijligenberg R, Rijkers GT, van Velzen­‑Blad H, et al. Dexamethasone and length of hospital stay in patients with community­‑acquired pneumonia: a randomised, double­‑blind, placebo­‑controlled trial. Lancet. 2011 Jun 11;377(9782):2023-30. doi: 10.1016/S0140-6736(11)60607-7. Epub 2011 Jun 1. PMID: 21636122. Go to original source... Go to PubMed...
  3. Snijders D, Graaff C de, Werf T van der, Boersma W. Effect of excluding ICU­‑admission on clinical outcomes in a randomized control trial studying the effect of corticosteroids in patients hospitalized with CAP. Eur Respir J. 2012;40(Suppl 56):P1734. http://erj.ersjournals.com/content/40/Suppl_56/P1734.abstract.
  4. Blum CA, Nigro N, Briel M, Schuetz P, Ullmer E, Suter­‑Widmer I, et al. Adjunct prednisone therapy for patients with community­‑acquired pneumonia: a multicentre, double­‑blind, randomised, placebo­‑controlled trial. Lancet. 2015 Apr 18;385(9977):1511-8. doi: 10.1016/S0140-6736(14)62447-8. Epub 2015 Jan 19. PMID: 25608756. Go to original source... Go to PubMed...
  5. Torres A, Sibila O, Ferrer M, Polverino E, Menendez R, Mensa J, et al. Effect of corticosteroids on treatment failure among hospitalized patients with severe community­‑acquired pneumonia and high inflammatory response: a randomized clinical trial. JAMA. 2015 Feb 17;313(7):677-86. doi: 10.1001/jama.2015. 88. PMID: 25688779. Go to original source...
  6. Wittermans E, Vestjens SMT, Spoorenberg SMC, Blok WL, Grutters JC, Janssen R, et al; Santeon­‑CAP Study Group; Members of the Santeon­‑CAP Study Group. Adjunctive treatment with oral dexamethasone in non­‑ICU patients hospitalised with community­‑acquired pneumonia: a randomised clinical trial. Eur Respir J. 2021 Aug 12;58(2):2002535. doi: 10.1183/13993003.02535-2020. PMID: 33446608. Go to original source... Go to PubMed...
  7. Villar J, Ferrando C, Martínez D, Ambrós A, Muñoz T, Soler JA, et al; dexamethasone in ARDS network. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. Lancet Respir Med. 2020 Mar;8(3):267-276. doi: 10.1016/S2213-2600(19)30417-5. Epub 2020 Feb 7. PMID: 32043986. Go to original source... Go to PubMed...
  8. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC, et al; Infectious Diseases Society of America; American Thoracic Society. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community­‑acquired pneumonia in adults. Clin Infect, DiS. 2007 Mar 1;44 Suppl 2(Suppl 2):S27-72. doi: 10.1086/511159. PMID: 17278083; PMCID: PMC7107997. Go to original source... Go to PubMed...
  9. Meduri GU, Shih MC, Bridges L, Martin TJ, El­‑Solh A, Seam N, et al; ESCAPe Study Group. Low­‑dose methylprednisolone treatment in critically ill patients with severe community­‑acquired pneumonia. Intensive Care Med. 2022 Aug;48(8):1009-1023. doi: 10.1007/s00134-022-06684-3. Epub 2022 May 13. PMID: 35723686; PMCID: PMC9208259.3 Go to original source... Go to PubMed...
  10. Coelho LM, Salluh JI, Soares M, Bozza FA, Verdeal JC, Castro­‑Faria­‑Neto HC, et al. Patterns of c­‑reactive protein RATIO response in severe community­‑acquired pneumonia: a cohort study. Crit Care. 2012 Dec 12;16(2):R53. doi: 10.1186/cc11291. PMID: 22449513; PMCID: PMC3681380. Go to original source... Go to PubMed...
  11. Monedero P, Gea A, Castro P, Candela­‑Toha AM, Hernández­‑Sanz ML, Arruti E, et al; COVID-19 Spanish ICU Network. Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study. Crit Care. 2021 Jan 4;25(1):2. doi: 10.1186/s13054-020-03422-3. PMID: 33397463; PMCID: PMC7780210. Go to original source... Go to PubMed...
  12. Dequin PF, Meziani F, Quenot JP, Kamel T, Ricard JD, Badie J, et al; CRICS­‑TriGGERSep Network. Hydrocortisone in Severe Community­‑Acquired Pneumonia. N Engl J Med. 2023 May 25;388(21):1931-1941. doi: 10.1056/NEJMoa2215145. Epub 2023 Mar 21. PMID: 36942789. Go to original source... Go to PubMed...
  13. Saleem N, Kulkarni A, Snow TAC, Ambler G, Singer M, Arulkumaran N. Effect of Corticosteroids on Mortality and Clinical Cure in Community­‑Acquired Pneumonia: A Systematic Review, Meta­‑analysis, and Meta­‑regression of Randomized Control Trials. Chest. 2023 Mar;163(3):484-497. doi: 10.1016/j.chest.2022. 08. 2229. Epub 2022 Sep 7. PMID: 36087797. Go to original source...
  14. Pitre T, Abdali D, Chaudhuri D, Pastores SM, Nei AM, Annane D, et al. Corticosteroids in Community­‑Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose­‑Response Meta­‑Analysis. J Gen Intern Med. 2023 Aug;38(11):2593-2606. doi: 10.1007/s11606-023-08203-6. Epub 2023 Apr 19. PMID: 37076606; PMCID: PMC10115386. Go to original source... Go to PubMed...
  15. RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. Dexamethasone in Hospitalized Patients with Covid-19. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. PMID: 32678530; PMCID: PMC7383595. Go to original source... Go to PubMed...
  16. Santacruz CA, Pereira AJ, Celis E, Vincent JL. Which Multicenter Randomized Controlled Trials in Critical Care Medicine Have Shown Reduced Mortality? A Systematic Review. Crit Care Med. 2019 Dec;47(12):1680-1691. doi: 10.1097/CCM.0000000000004000. PMID: 31567349. Go to original source... Go to PubMed...
  17. Inzucchi SE, Siegel MD. Glucose control in the ICU - how tight is too tight? N Engl J Med. 2009 Mar 26;360(13):1346-9. doi: 10.1056/NEJMe0901507. Epub 2009 Mar 24. PMID: 19318385. Go to original source... Go to PubMed...
  18. Umpierrez GE. Glucose Control in the ICU. N Engl J Med. 2023 Sep 28;389(13):1234-1237. doi: 10.1056/NEJMe2309442. PMID: 37754290. Go to original source... Go to PubMed...
  19. Dubois J, Van Herpe T, van Hooijdonk RT, Wouters R, Coart D, Wouters P, et al. Software­‑guided versus nurse­‑directed blood glucose control in critically ill patients: the LOGIC-2 multicenter randomized controlled clinical trial. Crit Care. 2017 Aug 14;21(1):212. doi: 10.1186/s13054-017-1799-6. PMID: 28806982; PMCID: PMC5557320. Go to original source... Go to PubMed...
  20. NICE­‑SUGAR Study Investigators; Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009 Mar 26;360(13):1283-97. doi: 10.1056/NEJMoa0810625. Epub 2009 Mar 24. PMID: 19318384. Go to original source... Go to PubMed...
  21. Klein Klouwenberg PM, Frencken JF, Kuipers S, Ong DS, Peelen LM, van Vught LA, et al; MARS Consortium *. Incidence, Predictors, and Outcomes of New­‑Onset Atrial Fibrillation in Critically Ill Patients with Sepsis. A Cohort Study. Am J Respir Crit Care Med. 2017 Jan 15;195(2):205-211. doi: 10.1164/rccm.201603-0618OC. PMID: 27467907. Go to original source... Go to PubMed...
  22. Balik M, Maly M, Brozek T, Rulisek J, Porizka M, Sachl R, et al. Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial. Intensive Care Med. 2023 Sep 12. doi: 10.1007/s00134-023-07208-3. Epub ahead of print. PMID: 37698594. Go to original source... Go to PubMed...
  23. McIntyre WF, Um KJ, Alhazzani W, Lengyel AP, Hajjar L, Gordon AC, et al. Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta­‑analysis. JAMA. 2018 May 8;319(18):1889-1900. doi: 10.1001/jama.2018.4528. PMID: 29801010; PMCID: PMC6583502. Go to original source... Go to PubMed...
  24. Meyhoff TS, Hjortrup PB, Wetterslev J, Sivapalan P, Laake JH, Cronhjort M, et al; CLASSIC Trial Group. Restriction of Intravenous Fluid in ICU Patients with Septic Shock. N Engl J Med. 2022 Jun 30;386(26):2459-2470. doi: 10.1056/NEJMoa2202707. Epub 2022 Jun 17. PMID: 35709019. Go to original source... Go to PubMed...
  25. Karvunidis T, Matejovic M. Rok 2022 v přehledu - Sepse. Anest. intenziv Med. 2022;33(5):256-259. doi:10.36290/aim.2022.040. Go to original source...
  26. Kjær MN, Meyhoff TS, Sivapalan P, Granholm A, Hjortrup PB, Madsen MB, et al. Long­‑term effects of restriction of intravenous fluid in adult ICU patients with septic shock. Intensive Care Med. 2023 Jul;49(7):820-830. doi: 10.1007/s00134-023-07114-8. Epub 2023 Jun 18. PMID: 37330928; PMCID: PMC10354110. Go to original source... Go to PubMed...




Anesteziologie a intenzivní medicína

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.