Anest. intenziv. Med. 2020;31(4):157-164 | DOI: 10.36290/aim.2020.034

One hundred and sixty years since isolation of cocaine and 115 years since synthesis of procaine - history of local anaesthetics and their pioneersReview Article

Málek J.
Klinika anesteziologie a resuscitace 3. lékařské fakulty UK a FN Královské Vinohrady Praha
Komise pro historii ČSARIM JEP

The article presents discovery of cocaine, its anaesthetic and stimulative effects, history of synthesis and use of other significant local anaesthetics as well as notable names connected with this history.

Keywords: history, local anaesthetics, cocaine, procaine, lidocaine, Karl Koller, William Halsted, Torsten Gordh.

Received: July 20, 2020; Revised: August 7, 2020; Accepted: August 13, 2020; Prepublished online: September 1, 2020; Published: September 18, 2020  Show citation

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Málek J. One hundred and sixty years since isolation of cocaine and 115 years since synthesis of procaine - history of local anaesthetics and their pioneers. Anest. intenziv. Med. 2020;31(4):157-164. doi: 10.36290/aim.2020.034.
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