Anest. intenziv. Med. 2015;26(3):152-155

Biological treatment and the risk of perioperative complicationsAnaesthesiology - Review articles

O. Gimunová1,*, O. Bednařík2, ©. Forejtová3
1 Klinika anesteziologie, resuscitace a intenzivní medicíny, FN Brno, LF MU
2 Interní hematologická a onkologická klinika, FN Brno, LF MU
3 Revmatologický ústav, Praha

So far, there is no consensus whether to stop biological treatment prior to elective surgery. The results of retrospective studies are very heterogeneous, because the retrospective study design and the relatively small numbers of individuals studied considerably limit the interpretation of the data. The risk of infection is greatest at the beginning of the administration of biological treatment. Current recommendations are in favour of interrupting biological treatment in the perioperative period. We present a recommendation on the management of biological treatment before surgery.

Keywords: biological treatment; perioperative period; infection

Received: January 18, 2015; Accepted: March 15, 2015; Published: June 1, 2015  Show citation

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Gimunová O, Bednařík O, Forejtová ©. Biological treatment and the risk of perioperative complications. Anest. intenziv. Med. 2015;26(3):152-155.
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    References

    1. Doran, M. F., Crowson, C. S., Pond, G. R., O'Fallon, W. M., Gabriel, S. E. Frequency of infection in patients with rheumatoid arthritis compared with controls: A population-based study. Arthritis Rheum., 2002, 46, p. 2287-2293. Go to original source... Go to PubMed...
    2. Goh, L., Jewell, T., Laversuch, C., Samanta, A. Should anti-TNF therapy be discontinued in rheumatoid arthritis patients undergoing elective orthopaedic surgery? A systematic review of the evidence. Rheumatol. Int., 2012, 32, p. 5-13. Go to original source... Go to PubMed...
    3. Listing, J., Gerhold, K., Zink, A. The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology, 2013, 52, p. 53-61. Go to original source... Go to PubMed...

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