Anest. intenziv. Med. 2012;23(5):237-241

Sugammadex from the perspective of evidence-based medicineAnaesthesiology - Review articles

Adamus Milan1,*, Herold Ivan2
1 Klinika anesteziologie, resuscitace a intenzivní medicíny Fakultní nemocnice a Lékařská fakulta Univerzity Palackého v Olomouci
2 Anesteziologicko-resuscitační oddělení, Oblastní nemocnice Mladá Boleslav, a. s.

Sugammadex is a novel drug for reversal of rocuronium or vecuronium-induced neuromuscular blockade. Compared to neostigmine, its mechanism of action (encapsulation) is not influenced by cholinesterase activity. In this article, the authors summarize the current indications of sugammadex, its advantages over neostigmine and its value in specific situations during anaesthesia.

Keywords: neuromuscular blockade; rocuronium; encapsulation; sugammadex

Received: July 10, 2012; Accepted: July 30, 2012; Published: October 1, 2012  Show citation

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Adamus M, Herold I. Sugammadex from the perspective of evidence-based medicine. Anest. intenziv. Med. 2012;23(5):237-241.
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