Anest. intenziv. Med. 2007;18(6):328-331

New findings in the field of neuromuscular transmission and neuromuscular blocking agentsAnaesthesiology

I. Herold
ARO, Oblastní nemocnice Mladá Boleslav, a. s.

The author summarizes recent developments in the field of neuromuscular transmision, the structure and function of the acetylcholine receptor and the introduction of new neuromusclar blocking agents in anaesthesiology and intensive care.

Keywords: neuromuscular transmission; suxamethonium; acetylcholine receptor; sugammadex; gantacurium

Published: December 1, 2007  Show citation

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Herold I. New findings in the field of neuromuscular transmission and neuromuscular blocking agents. Anest. intenziv. Med. 2007;18(6):328-331.
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    References

    1. Errikson, L. Evidence-based practice and neuromuscular monitoring: It's time for routine quantitative assessment. Anesthesiology, 2003, 98, p. 1037-1039. Go to original source... Go to PubMed...
    2. Lindstrom, J. Nicotinic acetylcholin receptors of muscle and nerves: Comparison of their structures, functional roles, and vulnerability to pathology. Ann. NY Acad. Sci., 2003, 998, p. 41-52. Go to original source... Go to PubMed...
    3. Jonsson, M. Nicotinic transmission and drugs in anaesthesia: Neuromuscular blocking agents and propofol-consequences for carotic body function. Karolinska Institutet : Stockholm 2006, 56 s., ISBN 91-7140-660-3.
    4. Jonsson, M., Dabrowski, M., Gurley, D., Larsson, O., Johnson, E., Fredholm, B., Errikson, L. Activation and inhibition of human muscular and neuronal nicotinic acetylcholine receptors by succinylcholine. Anesthesiology, 2006, 104, p. 724-733. Go to original source... Go to PubMed...
    5. Martyn, J., Durieux, M. Succinylcholine: new insights into mechanisms of action of an old drug. Anesthesiolgy, 2006, 104, p. 633-634. Go to original source... Go to PubMed...
    6. Fodale, V., Santamaria, L. The possible neuroprotective effect of laudanosine, an atracurium and cisatracurium metabolite. Acta Anaest. Scand., 2003, 47, p. 780. Go to original source... Go to PubMed...
    7. Chiodini, F., Charpatier, E., Muller, D., Tassonyi, E., Fuchs-Buder, T., Bertrand, D. Blockade and activation of the human neuronal nicotinic acetylcholine receptor by atracurium and laudanosine. Anesthesiology, 2001, 94, p. 643-651. Go to original source... Go to PubMed...
    8. Fodale, V., Santamaria, L. Drugs of anesthesia, central nicotinic receptors and postoperative cognitive dysfunction. Acta Anesth. Scand., 2003, 47, p. 1180. Go to original source... Go to PubMed...
    9. Moore, E., Hunter, J. The new neuromuscular blocking agents. Do they offer any advantages? Br. J. Anaesth., 2001, 87, p. 912-925. Go to original source... Go to PubMed...
    10. Belmont, M., Lien, C., Tjan, J., Bradley, E., Stein, B., Patel, S., Savarese, J. Clinical pharmacology of GW 280430A in humans. Anesthesiology, 2004, 100, p. 768-773. Go to original source... Go to PubMed...
    11. Caldwell, J. The continuous search for a succinylcholine replacement. Anesthesiology, 2004, 100, p. 763-764. Go to original source... Go to PubMed...
    12. Naguib, M. Sugammadex: Another milestone in clinical neuromuscular pharmacology. Anesth. Analg., 2007, 104, p. 575-581. Go to original source... Go to PubMed...
    13. Miller, R. Sugammadex: An opportunity to change the practice of anesthesiology. Anesth. Analg., 2007, 104, p. 477-478. Go to original source... Go to PubMed...
    14. De Boer, H., van Egmond, J., van de Pol, F., Bom, A., Booij, L. Reversal of profound rocuronium neuromuscular blockade by sugammadex in anesthetized rhesus monkeys. Anesthesiology, 2006, 104, p. 718-723. Go to original source... Go to PubMed...
    15. Sorgenfrei, I., Norrild, K., Larsen, P., Stensballe, J., Østregaard, D., Prins, M., Viby-Mogensen, J. Reversal of rocuronium-induced block by the selective relaxant binding agent sugammadex. A dose-finding and safety study. Anesthesiology, 2006, 104, p. 667-674. Go to original source... Go to PubMed...
    16. Kopmann, A. Sugammadex: A revolutionary approach to neuromuscular antagonism. Anesthesiology, 2006, 104, p. 718-723. Go to original source... Go to PubMed...
    17. Forel, J. et al. Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome. Crit. Care Med., 2006, 34, p. 2749-2757. Go to original source... Go to PubMed...
    18. Marini, J. Early phase of lung-protective ventilation: A place for paralytics. Crit. Care Med., 2006, 34, p. 2851-2853. Go to original source... Go to PubMed...

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