Anest. intenziv. Med. 1999;10(1):14-16

Trimecain in prevention of coughing after endoscopic ENT surgery in paediatric patientsArticles

T. Vymazal1, M. Marková2, E. Mikešová2
1 KAR 2. LF UK a IPVZ, Motol, přednosta doc. MUDr. Karel Cvachovec, CSc.
2 Klinika ORL 2. LF UK, Motol, přednosta doc. MUDr. Zdeněk Kabelka

We sought to determine the effect of intravenously administered trimecain (Mesocain 1%, Leciva, CZ) in strictly defined dose and time ofadministration to prevent coughing during recovery from general anaesthesia for endoscopic ENT surgery in paediatric patients. We also followedthe effect of IV trimecain on heart rate, blood pressure, capillary haemoglobin saturation and time to response to verbal command during recovery ofpaediatric patients. We found that administration of trimecain in the dose 1 mg/kg 2-3 mins before the end of general anaesthesia significantly reducesthe occurrence and intensity of coughing after instrumentation in upper and lower respiratory tract in paediatric patients, diminishing the risksassociated with this stage of operation. This amount of trimecain does not possess any adverse effects of hemodynamic parameters in hemodynamicallystable paediatric patients.

Keywords: cough; endoscopic ENT surgery; paediatric anaesthesia for ENT surgery

Published: February 1, 1999  Show citation

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Vymazal T, Marková M, Mikešová E. Trimecain in prevention of coughing after endoscopic ENT surgery in paediatric patients. Anest. intenziv. Med. 1999;10(1):14-16.
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