838
ABSTRAKTY3363200011158114164221282345406464520
Z3909200011151
KONGRESU3986200011156116178239299356406466
/4478200011132
CONGRESS4536200011154116177239299355406456
ABSTRACTS5018200011158114164221282345401459509
(LIVES)2480320097236080125166206229
Physiology27263200974287124156175220240284330369
is31123200971951
the31803200972671112
only33093200974489109147
polar34733200974691111150177
star3667320097315999126
we38103200975899
have39263200974483121161
–410432009740
unikátní41613200974489108146186213258277
akce44553200973977112152
proběhla46243200974673117163205250269308
již4949320097203974
potřetí50403200974591118144185212231
v528832009739
Praze53443200974268108143184
|5584190011126
123565419001113683130
/23748040010732
Anest24518040010752100145178207
intenziv267880400107196794136184221240282
Med.29798040010770115165181
2026;37(2):116-1253179804001074487129171186230271291334356370407442481511549587631
/38558040010731
ANESTEZIOLOGIE39528040010753112155200245290342362424467527586607650
A46248040010752
INTENZIVNÍ4698804001071978123168226276296345405426
MEDICÍNA51458040010770114174195248268327381
www.aimjournal.cz4258040010765133201214257275349367415463490539579598614654693
of42562001054770
the51962001052774117
models660620010572119167210228259
yielded94362001053958100118166208256
sufficient122462001053378101127146184202244291316
accuracy,156462001054180117163188228267308319
indicating190762001051865112130169209235252299346
its22786200105184578
generalizability238062001054891137180205246263281316357405423440458485526
supporting42576001053480130179228255286304352401
its8517600105194781
predictive95876001054976119168187227257275316359
capability134276001054182131172222241259277305347
to171476001052875
unseen181476001054896128172217265
samples.210476001053375148198217261294310
Studying244076001054167115164204224271320
the278576001052876120
samples,42590001053373144192210252284299
we’ve746900010563105120159200
noticed96890001054794120137176217265
that125490001052874113139
not141490001054894120
alone155690001054057104150193
airway17719000105395782147187224
pressure201790001054874115147179224249291
has232990001054786118
influence24699000105186486107153195242280321
on281290001054793
venous425104001054082129176223255
pressure704104001054975117150182228253295
levels,1023104001051962101143161193208
yet1255104001054082108
also138810400105405890137
a15491040010540
small16141040010533105144162180
increase1818104001051965105130172211243286
in2129104001051865
PEEP2218104001054584124167
contributes2410104001053985132158184202250297324366398
to2833104001052772
increase425118001051864103128170208240282
in730118001051864
CVP817118001055097141
Conclusions:981118001055095142180198244275292338385416431
Adjustments1434118001055298116161193220292334381406439
in1896118001051864
mechanical19831180010572115154200239285303341381399
ventilation2404118001054082128153171189227253271317364
parameters2790118001054989425132001052666137179206247272304
influence74713200105186486107153195241280321
CVP.1085132001055097141146
To1248132001054182
support1347132001053378126174221247276
personalized1640132001054992117150196243282300317352393441
approach,2098132001054088136161207247285332346
a24611320010540
data2518132001054887113152
driven268713200105487391131172218
approximator425146001054088136161207243261332371397441467
was9091460010564104135
trained106214600105275392110156198246
to1326146001052772
predict1415146001054975116164181220249
CVP1681146001055097142
levels.1840146001051961100141159191206
Rescuing4251700015381143197256329370446510
the9571700015351125184
failing11641700015348110152194236311375
circulation1562170001535697159218292332397448488553626
via22111700015362104169
humoral24031700015372143247312372436477
reset:4251840015359120174235288321
total7691840015351117169233275
plasma10671840015370109173227331395
exchange14851840015359126184258322397461519
in20271840015338114
refractory21631840015360121169231294352405471531596
post–cardiopulmonary425198001537013619024229936042348655859966473580784895210171090115412171282
bypass17301980015369132205269323378
mixed213019800153102144213273344
shock.24971980015351126190249323358
A4252120015382
case5302120015356120174235
series7882120015352113173215275329
Tudor4252330012455107167226264
Florin710233001245278137175203262
Borjog1,9922330012461119158186244304129223400733246
2,135023400733313852330012426
Adelina14312330012466125178207235294348
Iacob1,1799233001242882128185246203923400733220702330012426
Mihai21162330012485113172226254
Popescu1,23902330012458115175229273319377276423400733246
2,282223400733328562330012426
Mihaela4252460012485113172225279307361
Livia806246001245179132160213
Agapie1,10402460012465123176237265318135324700733246
2,141124700733314462460012426
Angelica14922460012466124183237266293339393
Bratu1,1905246001246099151188247214824700733246
2,220624700733322412460012426
Catalin4252590012460112149203231259318
Constantin7632590012460117176220257311370406435494
Badiu3,12772590012461114174202261153826000733215712590012426
Carmen16172590012460113151237291351
Orban1,19882590012472111170224283226526000733246
22323260007333
1Clinical425279007130453278001215881104159182227276299
Department7732780012167118175224256292375426481514
of1308278001215584
Anesthesia14132780012161117167207240296346385408456
and18902780012149104161
Intensive2072278001212479111161216255278326376
Care,24692780012158106139189208
University4682910012165120143191240273313336369419
Emergency9082910012150132183216271322377422472
Hospital14012910012165121160217240273322346
Bucharest17682910012154109154209257290339379413
2Department4253050071304563040012167118175223256292375425481513
of991304001215584
Anesthesia10963040012161116167206240295346385408456
and15733040012148104160
Intensive1754304001212480112161217256279327376
Care,21523040012158106138188208
University23813040012165120143192241273314337370420
Emergency4683170012149132182215271321377422471
Hospital9613170012165120160216240273322345
Bucharest,13273170012155110155210258290340379413434
„Carol1783317001213592140172227251
Davila”20553170012167115161185208256291
University23673170012165120143191240273314337370419
of468330001215584
Medicine5733300012181131189212257280335385
and9793300012149104160
Pharmacy,11613300012153107155188271320364414430
Bucharest16123300012154109155210258290340379413
3Clinical425344007130455343001215881104159182227276299
Department7753430012167118175224256292375426481514
of1310343001215584
Cardiovascular14153430012158107139195218273321369408453508531579612
Surgery,20483430012149104136192242275326342
University24113430012165120143191240273313336369419
Emergency4683560012149132182215271321377422472
Hospital9613560012165121160216240273322345
Bucharest13273560012155110155210258290340380413
Background:565384001054485124161208233279326372420435
Cardiopulmonary1016384001055090116162181227276323341412460507546572614
bypass-associated1646384001054886135176208241266306338370417457476515541582631
inflammation229338400105186588109149220292331358376423470
can2779384001053979126
produce425398001054873118165210249289
mixed729398001057188125166213
cardiogenic–vasodilatory957398001053978103149166212259301347364402437476515547593640658675714739783809850
shock,1822398001053277123162198215
characterized2052398001053884122147187225254294319337372412460
by2527398001054885
myocardial26273980010570107152191231255425412001054765104122
dysfunction563412001054786119143190236275304322369415
and994412001054086134
hypotension,1143412001054784133180206247294326343389436451
often161041200105466999140187
refractory181341200105256789116156195224269295337
to2165412001052772
conventional2253412001053984130168210256282300347393433451
vasoactive2719412001054080112159425426001054079109127167209
agents.650426001054088131178204238254
We9204260010572113
report1049426001052667116163190220
successful1285426001053378118155197230262286334352
rescue1653426001052668101140187230
use1899426001054678121
of2036426001054770
total212242600105287399140158
plasma2296426001054968107140211251
exchange2563426001054281119166205252300343
(TPE)425440001052367112152176
in617440001051864
three697440001052774100141185
patients898440001054888115133175222248282
with1196440001056382109156
this136844000105277491123
specific1507440001053380124164182205224264
type1786440001052769118162
of1963440001054770
shock.2049440001053379126166203220
Methods:22854400010568111138185232281313328
The2628440001054189132
first277644000105234268101129
patient425454001054888114132174220246
underwent686454001054692140182207273314360386
CABG10884540010549101145199
and1302454001054086133
PFO1451454001054382140
closure,1606454001053957103135180205247260
and1882454001053985133
required2030454001052667115161178203245293
the2338454001052773116
institution246945400105186496124142168214241259305352
of2837454001054669
V–A425468001054587138
ECMO579468001054191159218
for81346800105236995
separation924468001053376124164190230257275322369
from130946800105235096168
CPB,1493468001054993136151
with1660468001056382109156
pharmacological1832468001054895135161233272312357376423472490529569588
requirements2436468001052567116162180206247319362409435469
reaching425482001052669110151199217265315
a7674820010540
peak834482001054994135173
Vasoactive-Inotropic1033482001054685119167209250280299341384413434482531558585633683702743
Score1802482001054283129157200
(VIS)202848200105247393134158
of2213482001054772
136.2311482001054481125142
The2479482001054292136
second2642482001053377119166214264
received425496001052669109151170210253302
aortic753496001054188115146164204
and983496001054088136
mitral1145496001057391119146187206
valve1377496001054081100140183
replacement1586496001052668117137177217259331375423449
for206149600105237097
severe2184496001053377117159186228
regurgitation2438496001052669118165191239257285326353371419467
secondary425510001053376117162210258298324366
to810510001052772
infectious90151000105186588131171201219266314346
endocarditis;1265510001054390139186226267293340358386404437451
discontinuation173451000105486799139184232258277324370410437455502550
of2302510001054771
extracorporeal2391510001054382112138179218264291340388414456496514
circulation42552400105405884123171190230257276323372
was8235240010564105138
only987524001054896115155
achievable1168524001054081128147190231272321341384
through1579524001052775101148196245292
VA–ECMO1898524001054593138181232301361
support2286524001053379128178227254285
amidst25975240010540113132180213242
a28655240010541
profound425538001054975121144191238285333
catecholamine775538001053979106148188235282302341413431478521
requirement,1313538001052668116163181207249321364411438454
peaking1783538001054892132169189236284
at2083538001054067
a21665380010540
VIS2222538001054565104
of2343538001054770
306.2429538001054386130146
The2591538001054190133
third274053800105287593119166
patient425552001054989116135177225251
underwent702552001054693142185211278320367394
aortic1121552001054088114145163203
and1349552001054087136
mitral1510552001057291118145185204
valve174055200105398099139181
replacement1947552001052668117136176215257329373420446
for241955200105236996
combined2541552001053984157206225271315364
valvular42556600105408099139187205245271
stenosis.713566001053361103150198231248281297
CPB1027566001055094137
separation1181566001053377125166192233259278325372
was15715660010563104136
achieved1724566001054080127145188228270319
with2061566001056382110157
vasoactive2235566001054081113161201241271289329372
support2624566001053379127176225251281
reaching425580001052668107147194212259308
a7515800010540
peak810580001054892132169
VIS997580001054565105
of1120580001054771
78.1209580001054384101
Adjunctive1328580001055299118164211251281299339382
therapy1728580001052875118144185233272
including2019580001051865105123170218236283331
hydrocortisone2369580001054785133158205245291317347366398445493536
hemisuccinate425594001054790163181213259299337355402442468510
and953594001054087136
hydroxocobalamin1107594001054785132158204241288328374423463482522594612659
5g1784594001054390
were18935940010563106132174
uniformly2085594001054794112135182208281300339
administered2442594001054089161179226244276304346372414463
across425608001054080106152185217
the659608001052774118
entire793608001054390116135160203
patient1012608001054989116134177225251
series.1279608001053376102121164197214
Results:1509608001054588121167185213247262
Renal1787608001054588135175194
replacement1997608001052668117136176216257329373420446
therapy2460608001052774118143184233271
with2748608001056382110157
an425622001054189
in-line54162200105196896117136184229
hemadsorption797622001054893167208258292340368419447466515564
filter13886220010523446391134161
was15766220010565107141
initiated174462200105196786115134175202246296
upon2067622001054898147197
admission2291622001054090164183217251269318367
of2685622001054872
the2784622001052877122
first42563600105234369103131
patient,582636001054990117136179227253269
with877636001056483111159
a10626360010540
suboptimal1128636001053379128176226253272344384403
clinical155763600105405877124142182223242
response;1825636001052668102150199247279323338
given2189636001054866107150197
the2412636001052775119
persistent2557636001054893119153171203232274321348
hemodynamic425650001054791163211260300349389461479519
collapse,970650001053985105123163212245289303
a12996500010540
salvage136565000105337493133174223266
intervention165765000105196692134160204246294320339386434
with2117650001056483110158
therapeutic2301650001052775118144185234278325353372412
plasma27396500010548681081414256640010572112
exchange561664001054382121168208255303346
was9326640010563104136
commenced.1093664001053985157229273320360401450466
Serial1583664001054185111129169188
IL-6179566400105195876122
assays1942664001054072105146184217
confirmed2184664001053984132155175200273317366
a25746640010540
marked26386640010573112138176218267
reduction425678001052668117164203233252299346
in797678001051865
the888678001052774118
systemic1031678001053373107135177249267307
inflammatory136367800105196588111150222294334361407433475
burden,1864678001054896122169212259274
with2164678001056482110157
the2347678001052774118
expeditious2490678001054382131175224242270288335383415
down-titration425692001054896160208236264283311337379406424472520
of971692001054771
vasoactive1068692001054081115162204244274293333376
support1470692001053380129178227254285
and1781692001054087136
the1943692001052876119
discontinuation2088692001054967100140186234261280327374414441460508556
of2670692001054771
VA–2767692001054593138
ECMO.425706001054191160219233
This681706001054190108140
prompted845706001054875121193242269310359
the1228706001052774118
early1369706001054382108127166
deployment1559706001054791139158206244317361408434
of2016706001054771
TPE2110706001054187126
in2260706001051865
the2348706001052875118
subsequent2489706001053379128161204253299343390416
cases,425720001053980113156189205
with649720001056382110157
comparable825720001054085158206247273314362382425
outcomes:1269720001054794122159205278321354369
a16577200010540
significant171672000105335199146165188207247288335361
reduction2096720001052668117164204233252299346
in2462720001051865
IL-6254672000105195876122
assays2688720001053972105146184217
and425734001054087135
the584734001052774118
concurrent725734001053985132172219245271313361387
weaning11357340010564106146193211258306
of1465734001054670
multimodal15587340010572119137165183255303352392410
vasoactive1992734001053980113160201241270289329371
support2387734001053379127176224251281
to2691734001052873
the2788734001052774117
point425748001054997115162189
of639748001054770
sustained735748001053379111139180198245288337
hemodynamic1098748001054790162210259298346386458477516
stability.1639748001053362102151170188206234275287
Conclusion:1951748001055196144184202249281299346394408
TPE2384748001054187127
provides2536748001054975121161180228271304
a28657480010540
potentially425762001054894120161207232250288306323361
effective80176200105426490131171199217256297
salvage111376200105327290129168215257
therapy1385762001052773115140179226264
for166476200105226893
refractory177276200105266689115155193222266291332
post–cardiopulmonary2119762001054895127154194235274299345363408456502520590636682721746786
bypass425776001054988137178211244
mixed695776001057291130172221
shock,942776001053380128168206224
facilitating1191776001052465105124142160188229256274321370
quantifiable1587776001054895135182209227251271310359379422
humoral2035776001054794166214241282301
reset2362776001052668101145172
and2560776001054088136
rapid2722776001052667116135183
hemodynamic304762001054790163210259299347387459477516
stabilization.358762001053362102151169188206242283310328375423439
Controlled405062001055096143170196242261280323372
studies444662001053361108156175218251
are472162001053965107
needed485262001054891135184227276
in515262001051865
order524162001054773121164190
to545562001052772
formally30477600105237096169209227246285
define335576001054891114134181224
standardized360276001053362102149198237263311329365407456
indications,408176001051865114132172212239257304352384400
optimal450476001054796123142213253272
timing479976001052746118136183231
and505476001054087135
biomarker–guided521276001054968115187227253291304790001054369110161207226274317366
endpoints.343290001054390139187235254301327361378
Does30471140015382148209263
protective33331140015369129196248309367421461523583
mechanical393911400153102161220293357433474532596638
ventilation46001140015362121194245286328392443483548622
protect30471280015370130196249309368422
the34911280015351125184
brain?36981280015369130193235311367
Ralitsa30471490012459113141169206250304
Petrova1,33711490012459110148187246298351371615000733246
3,377415000733338071490012426
Ivelin3853149001242982134162190249
Karageorgiev1,41231490012461114153206265318377415475503556608473015000733246
3,478815000733348221490012426
Sevil30471620012454107160188216
Ahmed-Shieva1,32831620012466124210264325359411470498552604657393416300733239651620012426
Vasil40111620012464114158186214
Popov1,42451620012458115175234286453016300733245611620012426
Aneesha46071620012466124178232276335388
Bhambra2,50161620012460119173259320358411542716300733254611620012426
Ivaylo3047175001242982135186214272
Minev2,33391750012485114173226279361717600733250
33678176007333
1Technical30471950071303075194001215094139194249273317366390
University34861940012164119142191240273313336369419
of3926194001215584
Sofia,40311940012150105134160208229
Plovdiv4281194001215476131178234257305
Branch,4607194001215587136191236291312
Bulgaria49401940012154109133189237270293341
2Medical304720800713030782070012180131188212256305329
University34282070012164119142191240273313336369419
of3868207001215584
Plovdiv,3973207001215476131178234257305321
Bulgaria43152070012155110133189237270293341
3Center304722100713030782200012158107163195244277
for3376220001213085117
Competence35152200012158111195252303336385441486535
PERIMED40712200012153101154179259309375
2,4467220001215172
Plovdiv,4560220001215375130178233256305320
Bulgaria49022200012154109132189237269293341
Background:3187244001054484123159205230276322368416430
Protective3632244001054468114140180220249267306348
mechanical39952440010572114154200239285303341381399
ventilation4409244001054081128153171189228254272318365
(PMV)4789244001052366132176202
is5006244001051850
recommended50712440010526671071512232943363824303047258001054392
in3158258001051965
severe3243258001053376116158184226
traumatic348925800105275394140212252279298337
brain3845258001054975116135181
injury404625800105186583130156198
(TBI)4263258001052468114133156
due4438258001054894138
to4595258001052773
increased4687258001051966105131173213245289338
risk504425800105264577114
of5177258001054771
ventilator-induced5267258001054082130156174193233304727200105277197120138184231276315355403
lung3465272001051864109156
injury363627200105196482127152193
and3844272001053985132
ARDS.3991272001055194150189204
However,42102720010555101163204243284309320
low4545272001051864126
tidal468627200105274591130148
volumes4849272001053984103148218260292
and5156272001054085133
higher5304272001054663110156198223
PEEP3047286001054586127171
may32452860010573114153
induce3424286001051967116164204247
hypercapnia3697286001054887137182209248290339388407447
and4171286001054088138
impair4335286001051992142183202229
cerebral4590286001054082109152202229270290
venous4906286001054184132180229262
drainage,5194286001054975117136184225274318333
potentially3047300001054894120161206232249287305323360
worsening34223000010563108134166208254271317363
secondary3800300001053375114158204251290315355
brain4170300001054873113130176
injury.436130000105186381126151191202
Objective:45783000010558106124166205233251290331345
Machine49383000010567106145190208253295
learning524830000105186098123170187232279
recognition3047314001052666106150198243261287305351397
of3459314001054669
the3543314001052773115
interdependence367331400105186389129154200242289332378425467513552592
between4280314001054891117181223265311
cerebral4606314001053979104145192218257275
perfusion4896314001054891116141188219236282328
pressure5239314001054874114146178223248289
and3047328001054189139
mechanical32133280010573118160208249298317357399418
ventilation.3658328001054184133160180199240267287335384401
Methods40853280010570115143192241291324
and4436328001054189139
materials:46023280010574115142185212232272292325341
A49693280010553
retrospective504932800105266998125172206256301343374393434478
analysis3047342001054189130149189223242275
of3349342001054771
TBI3447342001054289108
patients3582342001054991118138181230257292
from390134200105235198172
the4100342001052876120
AmsterdamUMC42473420010552126160189231258307347421477546598
ICU4871342001051971127
Database5024342001055899127168218260293337
was53883420010565106140
conducted.3047356001053985133181228267297339388404
Intracranial347635600105196692118159199225266313331371389
pressure3891356001054875117150183229255297
(ICP)421335600105244292136158
and4396356001054087136
cerebral4557356001054081107149198224265284
perfusion4867356001054892118145192225243290337
pressure5230356001054975117150183229255297
(CPP),3047370001052372116159180194
along3260370001054059106154202
with3482370001056482110157
mechanical36593700010572115156203243290308348388407
ventilation4086370001053982129155174192232258277324372
parameters4477370001054990116156228272299341367400
(PEEP,4897370001052368107148191196
DP,51133700010557101106
Pplat,5239370001054492111151177193
I:E545237000105193475
ratio,304738400105266793112159173
RR,3242384001054590107
VT,3371384001054591101
Paw3494384001054484147
mean,36633840010572115155202217
FiO2,3902384001054159118158173
pO2,40973840010549109149164
pCO2,42833840010549100157197212
P/F4517384001054469111
ratio)465038400105266693111159180
and4852384001054087135
central5009384001054081128155181222240
venous5271384001054083130177224257
pressure,3047398001054975117150183229255297311
were33793980010563106132174
extracted.3573398001054382112138179219248290339355
These3948398001054190133166210
datasets4178398001054888114155188231258292
were44913980010563106132174
used4686398001054679122171
to4877398001052873
determine4971398001054891118160186259277324367
optimal535939800105469512314130474120010572112131
combinations3203412001053985158206225272312338357404452484
of3713412001054670
input3808412001051966114161189
features4023412001052365105131178204246279
for432841200105236996
identifying4449412001051967110157183202226268287334383
nonlinear4857412001054795142161179226269309334
patterns.5217412001054989116146188213261294310
To3047426001054183
model31494260010572120169212231
such3399426001053379119166
time3584426001052746118161
series3764426001053376102121164197
rich398042600105264585132
data,4131426001054888114155170
we43214260010563106
attempt444642600105406797138210259286
to4751426001052773
predict4843426001054975117166185224254
CPP5116426001055094137
recordings52724260010526681091551812283047440001051865114146
with3215440001056382109157
a33934400010540
TCN-Transformer3455440001054189145173210231272319351376422449521565591
hybrid4067440001054885135161180228
approach.4317440001054088137164210251291338353
It4692440001051946
is4760440001051850
an4832440001054087
architecture4941440001054066104151169197238279308355381423
that5386440001052775115141
combines3047454001053984156204222269311344
one-dimensional3407454001054693136164214232303346392424442488535575593
convolutional4016454001053984131169215234280307325372419458476
networks4508454001054790117182228254291327
(CNN)4850454001052472127182205
and5071454001053986134
a52204540010540
parallel5276454001054888114154172190233251
transformer.304746800105275394141174198245271344387413425
This3492468001054189108140
pipeline3651468001054967116160179197244287
model39574680010573120169212231
can4208468001053979126
process4354468001054875121161203236269
raw4642468001052667130
sequences4791468001053376125172215262302343376
to5187468001052773
extract5279468001054382112138179218248
hierarchical3047482001054765108134175201239286304344384403
temporal3468482001052769141189238264305323
features3809482001052366105132179205247280
and4107482001054087135
conveys4260482001053985133171214252286
the4564482001052774117
data4699482001054888115155
to4872482001052773
global4963482001054866113162203222
relational520348200105266887126153172219266306325
mapping,30474960010572112161210228275324339
which34054960010563111129168215
is3639496001051850
suitable370849600105337997125165214233276
for400349600105236996
processing4117496001054975121162203236269287334382
of4518496001054670
nonlinearity4607496001054794142160178225269308334353380422
in5047496001051966
bio-signals.5131496001054968115143177195243290330348380397
Results3047510001054486118163181208241
and3303510001053985133
Discussion:3451510001055674105144190221253270316363377
Analysis3843510001055197136154192224242273
of4131510001054669
the4215510001052773115
available4346510001053977117134152191238257299
patient4660510001054888114131173219245
datasets4920510001054786112151183225252285
suggests5220510001053378125172214246274307
a30475240010540
seasonal3103524001053376115148195242282301
inversely3420524001051865103146171205248267306
proportional3742524001054975121170218244274293340387427445
trend420352400105285496143191
in4410524001051865
airway449152400105405884150191229
pressure4736524001054875117150182228254296
levels5048524001051861101143162194
and5258524001054087135
the5409524001052775118
corresponding3047538001053985111138180213261309357405424471519
cerebral3585538001054081107149198224265284
perfusion3888538001054993119145193225243290338
levels4245538001051962102144163195
during4459538001054895121139186235
mechanical47135380010572116156203243290308348388407
ventilation.5139538001054082129156174193232259278325372388
Such3047552001054085124170
a32325520010539
time3286552001052745115157
series3458552001053375100118160192
trend366555200105275293139186
could3866552001053983129147194
be4075552001054891
a41815520010539
subject4235552001053378125143185224253
of4503552001054669
contribution4587552001053883129155180198245291318336382428
to5030552001052771
a51175520010539
secondary5171552001053275114158205252291316357
brain3047566001054976117136183
injury.325656600105196685132158201213
The3495566001054190134
evaluation3655566001054384125144191231258277324373
benchmarks4054566001054993141181229301342368406442
of4523566001054771
the4620566001052775119
deep4765566001054892136185
learning4976566001051963103129177196243292
model52945660010573121171214234
yielded3047580001053958101120168211260
sufficient3324580001053379103129149188207249297323
accuracy,3664580001054080118164190231271312324
indicating4005580001051865113132171212238257304352
its437458000105184680
generalizability,4471580001054891138182208248267285321362411430448466494536547
supporting5035580001053379127176224251281300347395
its544758000105184680
predictive3047594001054975118167185225255273314356
capability3429594001053980129170219238256274302344
to3799594001052773
unseen3898594001054794126170214261
samples.4185594001053374146195215258291307
Conclusions:4518594001055197144184203250282300347395428443
Adjustments49865940010552100118165198226299342390416450
in5462594001051966
PMV30476080010544111156
parameters3223608001054990115156228272299341366400
may36446080010572112150
influence381460800105196689111157200247287329
CPP4163608001055094137
and4321608001054087135
have4477608001054787126168
clinically466660800105395776122141180221239258297
relevant498360800105266887130170211258284
effects528860800105436693135176205240
on3047622001054693
brain3155622001054773113130176
injury.334662200105186482127152193204
To3565622001054081
support3661622001053377125173220245274
personalized3951622001054790115148194241279297315350390438
mechanical44046220010571114153199238283301339379397
ventilation4816622001053980126152169187226251269315362
and5193622001053985132
make53406220010571110146187
it3047636001051846
protective3118636001054975121148190230260278318361
not3504636001054794121
only3650636001054795113153
to3828636001052773
the3926636001052774117
lungs4068636001051966113161193
but4286636001054996124
also443563600105405890138
to4598636001052773
the4696636001052774118
brain,4839636001054875115134181196
a50606360010540
data5125636001054888114155
driven530563600105487493133175222
approximator3047650001054088137164210247266338378405450477
was35436500010563104137
trained369965000105275394112159203252
to3970650001052773
predict4062650001054975117166185224254
CPP4335650001055094137
and4491650001054087136
ICP4646650001051869113
levels.4778650001051962101144163195211
A30476740015382
distinct31526740015369110165218258334391445
phenotype36196740015370143202275340392455528589
of42316740015363112
critical43666740015356117159210251309373415
illness?4803674001533981122197256310364424
Clinical30476880015377117158234275333397439
profile35096880015370130196245288330389
and39216880015362137207
outcomes41516880015364136187246311414473527
of47016880015364113
hematological30477020015372132234299350415454519582623681745787
patients38577020015369133184224284357408462
admitted43417020015363133237279330382443514
to48787020015351117
the50177020015351125184
ICU52247020015340118198
Matilde30477230012485138175204232292346
da34137230012459113
Silva3546723001245482110163216
Drumond1,37837230012469108167253312371431421172400733242437230012426
Dúlio42897230012470129157185243
Teixeira45537230012454101130182234263301354
Passos2,49277230012458111154198256300522772400733252617230012426
Teresa30477360012455101141194238292
Silva3,3359736001245482110163216357573700733236097360012426
Mariana36557360012485139177205258317370
Silva4,4046736001245481109163216426273700733242967360012426
Maria43427360012485139177205258
Aguiar5,46207360012466123182210264302492173700733249547360012426
Lisandra3047749001245178122176235295334387
Gouveia6,34547490012468127186240291320373382975000733238627490012426
Gonçalo39087490012468127187232286314372
Faro43007490012453103141200
Silva7,4520749001245482110163216473475000733247637490012426
Guilherme30477620012468128156184243296335421475
Coelho8,35427620012460116170199258316385976300733238937620012426
Francisco3939762001245389141201246274318364422
Calisto9438176200124591121401682122493084689763007332