1637
NOVÁ3518202011159120179233
DOPORUČENÍ3777202011159121174237296355412467529562
/4365202011132
NEW4422202011159115199
RECOMMENDATIONS4647202011157113170232307382438500563621675708769831880
Komentovaný17183230974387155196241267311350389434471
souhrn22063230973277122167193239
doporučení24613230974690137182209254291331376395
Evropské28733230973978105149196228266306
společnosti31963230973177123142183221265310342370389
intenzivní3602323097196490130175211230269315334
medicíny395332309767108154174210229274311
(ESICM)42813230972362102121169234256
202345543230974182121163
pro47343230974572116
management486732309767106151190236277344385430457
ARDS53413230974992147186
|5584198011126
195565419801113685131
/23578043010732
Anest24348043010752100145178207
intenziv266180430107196794136184221240282
Med.29628043010770115165181
2023;34(4):184-1953162804301074487129173186231275300341363377414453499528567605648
/38558043010731
ANESTEZIOLOGIE39528043010753112155200245290342362425467527586607650
A46248043010753
INTENZIVNÍ4698804301071978123168227276296345405426
MEDICÍNA51458043010770114174195248268327381
www.aimjournal.cz4258043010765133201214257275349367415463490539579598614654693
Days4255540834578108135
Free580554083325286121
From721554083325289147
Mechanical8885540835490122160193231246278310326
Ventilation12335540833669107128144159191213228266305
Among15575540834199137176215
Patients1791554083366789104139177199226
With2037554083577496134
Acute21915540834172110132166
Respiratory2377554083357097136151172205227264286320
Distress27165540834661871101321664256540832653
Syndrome:4946540833363101141162199257292305
A81565408341
Randomized8736540833568106145184242257286320360
Clinical1249654083405570108123155188204
Trial.146965408333506698113126
JAMA.16126540832464119161176
201918056540833468100130
Mar19526540835487108
5;321(9):846-857.2076654083354580113144159192210222257293329353389423456462
doi:2555654083387691104
10.1001/2675654083346678109141177209230
jama.2019.0555.4257540831547105137151187221252283294329363395428440
PMID:8807540833589104150163
30776290;10597540833468101135167201235270283
PMCID:13587540833589129144190203
PMC6439595.15767540833589130164200233266300332367378
36.425853085367288
Writing529854083577893116131169208
Group7538540834365102140180
for948854083195678
the1042854083215994
Alveolar1152854083415789123162178210231
Recruitment13998540833570103124163178200258293332353
for1768854083185677
Acute18618540834173110133167
Respiratory2043854083367198137152173206228265286320
Distress2379854083466187110132166193219
Syndrome26148540833262101140161199257292
Trial42595408333506597113
(ART)554954083185995129151
Investigators;721954083155384118145168183222255276313335362374
Cavalcanti11119540834073104137153185218256277292
AB,1419954083417790
Suzumura15249540833370100138196233254287
ÉA,1827954083337690
Laranjeira1932954083326586119157173207222244277
LN,2224954083327790
Paisani2330954083356782108141179194
DM,254095408345100114
Damiani26709540834577135150182220235
LP,4251054083316772
Guimarães5151054083448297155187208241276303
HP,8361054083448084
et93810540833457
al.10131054083324760
Effect10911054083335271105138162
of127110540833757
Lung134610540833168106145
Recruitment151010540833570103124162177200258293331353
and188110540833170109
Titrated2008105408332497293126148182221
Positive22471054083357299114136151184218
End‑Expiratory248310540833371110132166199238254275308330367388422
Pressure4251154083355690117143181202236
(PEEP)6751154083185486119154172
vs86111540833259
Low93411540833168120
PEEP106811540833567100135
on121711540833776
Mortality130711540835493114139172187202224258
in157911540831553
Patients16461154083356789104139177198226
With18861154083577496134
Acute203411540834173110133167
Respiratory22151154083357097136151173206227264286320
Distress25491154083456187110131166192219
Syndrome:2782115408333621014251254083386097156192204
A650125408341
Randomized71212540833669107147185244259289323363
Clinical10961254083405570109124156190205
Trial.1322125408333506698114127
JAMA.147012540832464120163178
2017166812540833569101131
Oct182012540834780104
10;318(14):1335-1345.19451254083356679115146177197229260278290320350383417439470501536569582
doi:25471254083397793105
10.1001/26731254083346679110142178210232
jama.2017.14171.42513540831547105137151187221252282288319350380410442451
PMID:89213540833589104150163
28973363;107013540833468102135169202237271282
PMCID:136713540833689130145191204
PMC5710484.158613540833589129165198231262299335371383
37.4251453085367079
Cutuli5161454083407698136151166
SL,6941454083336377
Grieco7831454083446581115147184
DL,9801454083457790
Michi108314540835469101138153
T,124914540833241
Cesarano13031454083397399132153186224262
M,157714540835468
Rosà165714540833573100133
T,180214540833341
Pintaudi18561454083354987108141178217232
G,210014540834457
et217014540833355
al.22381454083324760
Personalized23101454083356889116154192224240254283317356
Respiratory267914540833569961351501712044251554083215879113
Support55115540833269108147185206231
in79415540831552
ARDS:85915540834176122154166
A1037155408341
Physiology‑to‑Bedside109115540833572102129143181196234273305326348385408445480519545559598632
Review.173615540833569101117151202212
J1961155408324
Clin19981554083395469106
Med.211715540835489128141
2023227015540833468101135
Jun24181554083246199
21;12(13):4176.25291554083346573103133150181211227239273303332364377
doi:4251654083387692104
10.3390/jcm12134176.5441654083346678114147180216240256288346376405436465500530558590602
PMID:116016540833588103148161
37445211;13341654083356696132164197227254262
PMCID:161016540833588128142187199
PMC10342961.182316540833689128160191223258290323358387396
38.4251753085367187
Sarge5241754083326585122157
T,69217540833341
Baedorf‑Kassis74517540833567101140177198219239275308333359373399
E,115517540833345
Banner‑Goodspeed121217540833568105142176197216262300338376402440475510548
V,177217540833644
Novack182717540834583114146177207
V,204517540833644
Loring21011754083316888103141179
SH,22911754083337688
Gong239117540834381119157
MN,256017540835499111
et268317540833455
al;27501754083324657
EPVent-228191754083326742518540833668105126145175
Study6121854083325390128160
Group.78318540834465101139177189
Effect9841854083335170103135159
of115518540833755
Esophageal12221854083336097136174206244278309324
Pressure‑guided15581854083355588114140177197230253293330344382416455
Positive20251854083357197111133148180213
End‑Expiratory225018540833270108129163195234249269301322359379413
Pressure26751854083355588114140177197230
on42519540833775
Survival5181954083326989123138170202217
from7531954083183976134
Acute90419540834172109131164
Respiratory10861954083356995134148169201222258279313
Distress14161954083466086108129162189214
Syndrome:164819540833362100138159195253287299
A1964195408341
Risk‑based20231954083355076105124164196222256295
and233519540833270108
Mechanistic246119540835488120158189227241266289303335
Reanalysis28131954083367042520540833269101115146173187212
of65120540833856
the7212054083225994
EPVent-282920540833267103135172193212242
Trial.1085205408333496495110122
Am122120540834199
J1334205408324
Respir13722054083356995134149169
Crit1555205408340607597
Care16662054083407292126
Med.180620540835489127140
2021196020540833467100130
Nov210420540834583114
15;204(10):1153-1163.22322054083346373108141177195226257275286315342371404425455482512545557
doi:28032054083387691102
10.1164/rccm.202009-3539OC.4252154083346577107134164200224243274304361373409442474508543578601632665697729777818830
PMID:126921540833588103148161
34464237;144421540833468105140176208242273282
PMCID:174021540833588128142187200
PMC8759303.195421540833588128162194226258290323356368
39.4252253085377488
Marini54222540835690112129168184
JJ,7552254083255063
Gattinoni84722540834579102127144183223263279
L.115522540833247
Time123122540833351111148
Course140822540834179119141170206
of164322540833959
Evolving173122540833467106123156173213253
Ventilator‑Induced201322540833771111133150166199222260283303321360401440474509550
Lung259222540833271111151
Injury:277222540831555711104252354083215670
The51623540833474110
„Shrinking6482354083215594116132170201218257297
Baby96623540833771111143
Lung“.113023540833371110150172181
Crit13322354083416379102
Care14552354083417597131
Med.160823540835692133146
2020177623540833570103138
Aug;48(8):1203-1209.193623540834280120132168205224259277289320350385419442473504539575586
doi:25442354083397894106
10.1097/26712354083366881112144180214235
CCM.0000000000004416.42524540834077132145180215250286321357392427463498534569605641671701714
PMID:115324540833588103148160
32697492;13272454083346699132164194226259270
PMCID:161124540833588128143188200
PMC7217130.182524540833588128162196227255287316350362
40.4252553085367387
Constantin52925540834076114140162194231252267304
JM,8502554083247891
Jabaudon9572554083245694127163202239277
M,125025540835568
Lefrant13342554083326583105137174195
JY,15462554083245967
Jaber16292554083245694129150
S,179525540833345
Quenot185625540834785119156194215
JP,20882554083245963
Langeron216725540833264102140174195231269
O,245325540834657
et252625540833456
al;25982554083324758
AZUREA267225540834180123159192234
Network.42526540834478100152189209239253
Personalised6892654083356788114151188220234248273307346
mechanical104626540835791123160191228242273305320
ventilation137726540833265102123137151182203218255292
tailored1680265408322546882119140173212
to190326540832157
lung19722654083145188126
morphology210926540835794115154191229244281319350
versus24712654083316485111147172
low265526540831452101
positive2768265408338761021164252754083223668101
end‑expiratory53827540833471109131167197236251271303324361381415
pressure9642754083396093119145181202235
for12102754083195676
patients12982754083397192106140178198225
with15352754083506587124
acute167127540833263100122155
respiratory18372754083215480118133154186207243264297
distress21462754083385277100120154180206
syndrome23632754083265896134155191249283
in265727540831552
France27212754083325183120152185
(the4252854083193976111
LIVE5472854083324682116
study):6742854083274986125156173184
a870285408332
multicentre,91428540835794108130145176209246267288321332
single‑blind,12582854083264077116130164187226241256293331343
randomised16132854083205390128166223238263297336
controlled196128540833167105126147183198213247286
trial.2258285408322435889103116
Lancet238528540833264102133166188
Respir25842854083367096134149170
Med.276528540835589128140
20194252954083346696125
Oct;7(10):870-880.56129540834677100112143158189219236246280311343365399433467478
doi:1050295408338748899
10.1016/S2213-2600(19)30138-9.11602954083346475104134164194218249281314344372393422454488523541571600617648681711740773794827837
Epub200829540833269106143
201921622954083346697125
Aug229829540834076113
6.242229540833446
PMID:247829540833587101145157
31399381.26462954083346391123157188221251260
41.4253053085366879
Chen51930540834077111149
L,68230540833144
Del7403054083458095
Sorbo8493054083327091130168
L,103130540833144
Grieco10893054083446580114146182
DL,12853054083457790
Junhasavasdikul13883054083256299136168194226257289315354368397435450
D,185230540834555
Rittayamai1921305408335507296128158190247279293
N,222830540834557
Soliman22993054083327085100157188226
I,253830540831527
et257930540833456
al.26493054083314658
Potential27213054083357193126163425315408322366882
for5253154083185576
Lung61831540833168105143
Recruitment77931540833569101122160174196253288325346
Estimated1142315408333608297154185206239278
by143831540833869
the15243154083225994
Recruitment‑to‑Inflation163531540833570102122160174196253288325346365387423446461499516532564585600637675
Ratio23273154083356788103140
in248531540831451
Acute255431540834172109130163
Respiratory273531540833569961341494253254083215374110131164
Distress6043254083456085108129162188214
Syndrome.83232540833362100138159195253287299
A1145325408341
Clinical12003254083405569106121152184199
Trial.1413325408333496495110122
Am154932540834199
J1662325408324
Respir17013254083356995134148169
Crit1884325408340607597
Care19953254083407293126
Med.213632540835488127140
2020229032540833468100133
Jan24383254083245592
15;201(2):178187.254532540833463731081411721862202372482773063394253354083346497102
doi:5413354083387690102
10.1164/rccm.201902-0334OC.6573354083346577107134164200224243273303361373409442473503538570589626658691725773814826
PMID:149733540833689103148161
31577153.16723354083346493126160192221253265
42.4253453085367085
Mlček52534540835469101133163
M,70334540835568
Otáhal78634540834770102139171186
M,98734540835567
Borges10703454083357394131165191
JB,12773454083245971
Alcala13643454083415587119134165
GC,15453454083438395
Hladík16563454083445990128143174
D,184534540834556
Kuriščák19163454083357192107132163195225
E,215634540833345
et221734540833455
al.22883454083314658
Targeted23623454083325980117152173206245
lateral26223454083154768101121154168
positioning280634540833877425355408326406277114152166203241
decreases68535540833872104125158190215250276
lung9803554083145189127
collapse1126355408331678297128167193227
and137235540833169107
overdistension149835540833768102123160174200222255293318332370407
in192435540831552
COVID-19-associated199535540834084119135180203233263286317343369407439453484505538577
ARDS.259135540834176122154166
BMC277635540833590129
Pulm4253654083357286143
Med.58536540835489128140
20217423654083346799130
Apr88936540834180100
24;21(1):133.10063654083346577111142156187201212241270302314
doi:13373654083387690102
10.1186/s12890-021-01501-x.14553654083356577107134165199224247277306339372407431467499530548584616645678709727757770
PMID:224236540833588102148160
33894747;241936540833466100133168200230261270
PMCID:270636540833588128142187199
PMC8065309.42537540833588128162196232265297331365375
43.4253853085367185
Fan5273854083326198
E,64338540833245
Wilcox7053854083577387118155184
ME,90638540835587100
Brower10233854083355693143177197
RG,12373854083367992
Stewart13463854083335386137169189213
TE,15763854083336679
Mehta167238540835489126147179
S,186838540833345
Lapinsky193038540833164103117155180209243
SE,21903854083326476
et228338540833456
al.23563854083324659
Recruitment243238540833569101122160174196253288325346
maneuvers27953854083578942539540833872110142176196223
for6673954083195677
acute76339540833264101123157
lung9393954083155289128
injury:10863954083155267104125158171
a1276395408332
systematic13273954083275985108141199231252267298
review.16443954083215587102136187197
Am186039540834299
J1978395408325
Respir20223954083357096135150170
Crit2212395408340607597
Care23283954083417394127
Med.247439540835590129141
2008263539540833468103138
Dec279339540834580112
1;178(11):1156-63.4254054083344271100132151182209222234263290319353375412445457
doi:8964054083387590101
10.1164/rccm.200802-335OC.10114054083356577107134165200225244274304361374409443478513547580599631663695742782795
Epub182040540833270108146
2008198040540833568103138
Sep213240540833367105
5.225140540833446
PMID:231140540833588103148160
18776154.24854054083346497131162191221255267
44.4254153085367488
Hodgson52841540834482121159184222260
CL,8024154083407184
Tuxen9004154083336596129167
DV,10814154083458088
Davies118441540834577107122156183
AR,13814154083417689
Bailey1485415408335678296130161
MJ,16604154083558091
Higgins17664154083445896135149186212
AM,199241540834196109
Holland21154154083448297112143180219
AE,23484154083417386
et244841540833456
al.25184154083324659
A2591415408341
randomised264641540832153911291662242384254254083266099
controlled54142540833167105126147183198213247286
trial843425408322435789103
of96342540833756
an103542540833269
open112142540833776111148
lung12864254083155189127
strategy14304254083264869101122155194226
with16724254083516587125
staircase1813425408326498195116146178204238
recruitment,20684254083215486106144158180238272309330343
titrated2427425408322375879111132165204
PEEP26484254083356799133
and279842540833169107
targeted4254354083215373110144165198236
low67243540831552102
airway7854354083324666118150180
pressures9764354083385992117143179199232258
in124543540831551
patients13084354083387090105138175196222
with15424354083506486123
acute16764354083326399121153
respiratory18414354083205379117131151183204240260293
distress2145435408338527799120153179204
syndrome.23604354083265895133153190246280292
Crit2663435408339597495
Care.27704354083397191124135
2011;15(3):R133.4254454083346798125133162191208241258269304336365397409
doi:8454454083387690102
10.1186/cc10249.9584454083346577107134164199223251281311342374405437448
Epub141744540833371108147
201115754454083346899126
Jun17124454083246199
2.182244540833446
PMID:188044540833588102147160
21635753;20514454083346595128160193225257268
PMCID:233044540833688128142187200
PMC3219001.254144540833588128163195225255290325356365
45.4254553085367185
Hodgson52545540834482121159184222260
CL,8004554083407184
Cooper89945540834077115153188209
DJ,11234554083466779
Arabi12174554083416294132147
Y,138045540833542
King14384554083355088126
V,157945540833644
Bersten16394554083356990117139172209
A,186445540834154
Bihari19344554083355087119139154
S,210345540833345
et216345540833456
al.22344554083324759
Maximal230945540835486117132189220235
Recruitment255945540833670102123160175196254288325346
Open42546540834889125163
Lung60846540833370109148
Ventilation77746540833669108130145160193215230269308
in110546540831553
Acute117846540834274113135170
Respiratory13684654083367199138154175209230268290324
Distress17124654083476289112134168195222
Syndrome195446540833464103143164202262297
(PHARLAP).227146540831955100142178211255291309320
A2611465408342
Phase267346540833674107134169
II,28624654083153143
Multicenter42547540835694109131146179213251273307328
Randomized77347540833669107146185244259288322362
Controlled115547540834178117138160197213228263303
Clinical14784754083415671109124156189204
Trial.1702475408333516698114126
Am1848475408342101
J1968475408325
Respir20134754083367198137153174
Crit2207475408340617799
Care23264754083417495130
Med.247547540835691131144
2019263947540833569101131
Dec279047540834782115
1;200(11):1363-1372.4254854083344276109145164195222235247276305339372393423452484517529
doi:9684854083387690102
10.1164/rccm.201901-0109OC.10844854083346576106133164200224243273303361373408442473502537569587623654685719767808820
PMID:191848540833588103148161
31356105.20924854083356594126160190220254265
46.4254953085367388
Kung53249540833571109147
SC,6984954083327284
Hung80149540834481119157
YL,9774954083356780
Chen107649540834077111149
WL,124449540835789102
Wang136549540835788125163
CM,154749540834095107
Chang167349540834077109146184
HC,18764954083448597
Liu19924954083314683
WL.209349540835890103
Effects22154954083325069103135158185
of241949540833856
Stepwise24944954083335386125175190215249
Lung276249540833268105144
Recruitment42550540833570102122160174196253288325346
Maneuvers78550540835486123158195227260281307
in110650540831552
Patients11725054083356687102136173194221
with14075054083506587125
Early15455054083336586101132
Acute169150540834171109130163
Respiratory18685054083367096134149170202223259280313
Distress21955054083466086108129162189214
Syndrome:242350540833362100138159195253287299
A2736505408341
Prospective,2791505408335559142551540832767103136161176210245257
Randomized,70251540833670108148187247262292327367380
Controlled110251540834179118140162200216231267307
Trial.1430515408333506699114127
J1578515408325
Clin16235154083415671110
Med.175351540835692132146
2019191951540833570102133
Feb207251540833468108
10;8(2):231.22015154083356780116135170188200236271303312
doi:25345154083397893106
10.3390/26605154083356780116150183220245
jcm8020231.42552540831546104138173205238270304335343
PMID:78252540833588103148161
30744214;9575254083346799129165197228258270
PMCID:124052540833689129143188200
PMC6406466.145452540833588128161197232267303339373386
47.4255353085367078
Kung52253540833572109147
SC,6895354083327284
Hung79353540834481118157
YL,9695354083356780
Chen106853540834078112150
WL,123753540835789102
Wang135853540835889126164
CM,154253540834094107
Chang166853540834077109147185
HC,18725354083448597
Liu19885354083324683
WL.209053540835890103
Effects22125354083335170104136159187
of241853540833756
Stepwise24935354083325386125175190216250
Lung276253540833268105144
Recruitment42554540833570102122160174196253288325346
Maneuvers78554540835486123158195227260281307
in110654540831552
Patients11725454083356687102136173194221
with14075454083506587125
Early15455454083336586101132
Acute169154540834171109130163
Respiratory18685454083367096134149170202223259280313
Distress21955454083466086108129162189214
Syndrome:242354540833362100138159195253287299
A2736545408341
Prospective,2791545408335559142555540832767103136161176210245257
Randomized,70255540833670108148187247262292327367380
Controlled110255540834179118140162200216231267307
Trial.1430555408333506699114127
J1578555408325
Clin16235554083415671110
Med.175355540835692132146
2019191955540833570102133
Feb207255540833468108
10;8(2):231.22015554083356780116135170188200236271303312
doi:25345554083397893106
10.3390/26605554083356780116150183220245
jcm8020231.42556540831546104138173205238270304335343
PMID:78256540833588103148161
30744214;9575654083346799129165197228258270
PMCID:124056540833689129143188200
PMC6406466.145456540833588128161197232267303339373386
48.4255753085367389
Kacmarek53357540833568100157189210243273
RM,82557540833691103
Villar948575408335516680112132
J,110057540832435
Sulemanji11555754083326984118175207245259274
D,144857540834556
Montiel152357540835592130151166200215
R,175757540833649
Ferrando18255754083336687108141178217254
C,209857540834153
Blanco21705754083365182120151188
J,237757540832436
et243257540833456
al;25075754083324758
Open258457540834786121159
Lung276257540833168106144
Approach42558540834282123145183216249288
Network.73358540834682105159198220251266
Open101958540834889125164
Lung120358540833370109149
Approach137258540834383123145183217250289
for16815854083195779
the17805854083236297
Acute189858540834274112135170
Respiratory20885854083367299139155176210232270292327
Distress24355854083476289112134169196223
Syndrome:26795854083336310314316420342559540835792103
A545595408341
Pilot,6035954083354963101122134
Randomized75459540833567105143181238252281314353
Controlled112459540834076114135155192207221256294
Trial.1435595408333496495110122
Crit1574595408340607597
Care16875954083407293126
Med.183059540835489128140
201619875954083346798129
Jan;44(1):32-42.21325954083255693105139175194225238249284316335371403415
doi:25645954083387590101
10.1097/26825954083346577107138172204224
CCM.0000000000001383.42560540834077132145180215250286321357392427463498534569600629663696708
PMID:114760540833588103148161
26672923.132160540833568102135168202234268280
49.4256153085367184
Xi52661540833853
XM,59661540833893105
Jiang7196154083243870107145
L,88261540833144
Zhu94461540833774111
B;107361540833546
RM113761540833590
group.12446154083385995133171183
Clinical14446154083405569106121152184199
efficacy1660615408334527088119151183215
and189361540833269107
safety20186154083265876110132165
of220061540833756
recruitment22746154083205486106144158180237272309330
maneuver262161540835889127161198230263284
in42562540831552
patients4976254083397193108142180201229
with7456254083516688126
acute89162540833263101123157
respiratory10676254083215581120135156188210246268301
distress13886254083385379102123156183209
syndrome16176254083265897136156193251286
using19236254083376378115154
low209662540831553104
tidal22206254083213675107122
volume23616254083326985122180215
ventilation:259562540833266104125140155187208223261299310
a425635408332
multicenter46963540835895109131146177210247268301322
randomized8036354083215391129166224238267300339
controlled115563540833167105126146183198213247285
clinical1453635408331466097112143175190
trial.1656635408321425788103115
Chin17846354083407791128
Med192563540835489128
J2065635408324
(Engl).21026354083195188126141160170
201022846354083356899130
Nov;123(21):31005.24266354083458311412615618521923727030031432536039042145642564540833445
PMID:48464540833588103148161
21162963.6596454083346592122155188223256268
50.4256553085367286
Guérin53165540834482116137152189
C,73965540834053
Reignier8116554083367085123161175209230
J,106065540832436
Richard11156554083365182120151172210
JC,13446554083246577
Beuret144065540833670108128162184
P,164365540833539
Gacouin170165540834476108145182197234
A,195465540834255
Boulain202865540833674111126158173210
T,225765540833341
et231765540833456
al;23926554083324758
PROSEVA246965540833670118150182219257
Study27456554083335391130161
Group.42566540834465101139177189
Prone6266654083365692130164
positioning80366540833877103117138153190228242280318
in113466540831451
severe11986654083266192126146180
acute139066540833264101122155
respiratory15586654083215480119133154186207243264298
distress18686654083385378101121155181207
syndrome.20876654083275897135155192249284295
N2395665408345
Engl245266540833370108123
J2588665408324
Med.262466540835589128140
201327776654083346899128
Jun4256754083246199
6;368(23):2159-68.5386754083344580113148166200234250261296327356388410447482494
doi:10466754083387691102
10.1056/NEJMoa1214103.11626754083346577107138171205229274307333387424457486515546576606636669681
Epub185767540833270108146
201320176754083346899128
May215967540835586116
20.22896754083356880
PMID:238367540833588103148160
23688302.255767540833468102137171205239271283
51.4256853085366980
Gattinoni5176854083437596120134171208246260
L,78868540833244
Tognoni84468540833265104141178216230
G,108668540834356
Pesenti11536854083356894128165185200
A,136468540834154
Taccone14306854083325990120156194228
P,166968540833539
Mascheroni171968540835586112143180214235271308323
D,205368540834555
Labarta212068540833163102134154178210
V,234168540833644
et239668540833455
al;24636854083314657
Prone‑Supine25316854083355591129163184215251289304341375
Study4256954083325390128160
Group.59969540834465102139177189
Effect8036954083335170104136159
of97769540833756
prone10476954083396096134168
positioning123069540833977103117139154191229243280318
on156369540833775
the16536954083225993
survival17616954083266383117132164196211
of198769540833756
patients20576954083397192107141178199226
with22986954083516587125
acute243769540833264101123156
respiratory26076954083215481119134154186207244265298
failure.425705408318506478114134166177
N613705408344
Engl66870540833269106120
J799705408324
Med.83470540835387125137
200198270540833366101131
Aug112470540834076113
23;345(8):568-73.12487054083346777111145176193225242253286319353375404437448
doi:17077054083387489100
10.1056/NEJMoa010043.18177054083346476105135168200224268300325379416447481511542576611642653
PMID:248170540833587101145157
11529210.26497054083346089120153185215245256
52.4257153085366984
Guerin52071540834380114134148185
C,71671540833951
Gaillard7787154083437589103117148168205
S,99471540833243
Lemasson104871540833164121152177202239277
S,133571540833344
Ayzac13907154083416999131162
L,156371540833144
Girard16187154083435777109129166
R,179571540833547
Beuret185371540833569106126158180
P,204471540833438
et209371540833455
al.21597154083314557
Effects22277154083325069102134157183
of242171540833755
systematic24877154083265783105137194225245260290
prone2788715408339599542572540833872
positioning51072540833977103117139154191229243280318
in84272540831552
hypoxemic90772540833868107145175208265279311
acute123172540833263100122155
respiratory14007254083205480118133153186207243264297
failure:1711725408318516580116137170182
a1907725408331
randomized19527254083205390128166223238266300338
controlled230472540833167105126147183198213247286
trial.2603725408322425789103116
JAMA.273272540832463118160174
200442573540833468103139
Nov57773540834583114
17;292(19):2379-87.7057354083346372106140172189220249266278312346378410433468501506
doi:12257354083387690102
10.1001/jama.292.13417354083346576106137173204225240272329360373408442474486
19.18417354083346474
2379.19297354083346899132142
PMID:208573540833588103148161
15547166.22607354083346395129161192223258270
53.4257453085367084
Mancebo52874540835486124155188227265
J,81174540832435
Fernández8647454083336686124156193232266295
R,117774540833548
Blanch12437454083365182120151188
L,144974540833245
Rialp1512745408335508196134
G,166474540834457
Gordo173974540834381102140177
F,193474540833338
Ferrer19907454083326686107141161
M,216974540835567
et225474540833456
al.23287454083324659
A2405745408341
multicenter246474540835794108130145176209246267300321
trial2803745408321425788103
of42575540833756
prolonged4967554083396096112149187225259298
prone8107554083385996134168
ventilation99375540833266103124138153184205220257295
in130475540831451
severe13717554083266092126146179
acute156675540833263100122155
respiratory17377554083205480118133153186207243264297
distress20507554083385278100121154180206
syndrome.22727554083265896134155191249283295
Am258275540834198
J2696755408324
Respir27367554083356995134148169
Crit304755408340607597
Care3161554083407292126
Med.33045540835489127140
200634615540833467103138
Jun3616554083246199
1;173(11):1233-9.373255408334417199133150181208222233262291325358379413423
doi:4172554083387691102
10.1164/rccm.200503-353OC.4291554083346577107134164200224243274304361374409442478511545577598630662694741781794
Epub51025540833371108147
200652665540833467103138
Mar54215540835486106
23.3047654083346880
PMID:31416540833588103148160
16556697.3315654083346598130163198231264269
54.3047753085367287
Taccone3151754083336091121158195230
P,33987540833539
Pesenti3454754083356894128165186201
A,36727540834154
Latini3743754083326586100137152
R,39127540833548
Polli3977754083367287101115
F,41107540833237
Vagginelli41647540833666105143157195229244258272
F,44537540833338
Mietto45087540835569103125148185
C,47107540834052
et47797540833456
al;4852754083314657
Prone‑Supine4926754083355592129164186217254292307344378
II53217540831530
Study5368754083325390128159
Group.30478540834465101139177189
Prone3253854083355591129163
positioning34338540833977103117139154191229243280319
in37688540831552
patients3837854083397192107141178199226
with4080854083516587125
moderate42228540835795133168188220241275
and45138540833270108
severe4638854083266092125146179
acute48348540833263101122155
respiratory5006854083215481119134154186207244265298
distress5321854083385278100121154180206
syndrome:3047954083265896134155191249283295
a335895408332
randomized3406954083215390129166224238267300339
controlled37619540833167105126147183198213247286
trial.406395408322425789103115
JAMA.41959540832463118159173
200943849540833468103138
Nov45389540834482113
11;302(18):1977-84.4667954083356269103137169186217247265276305335367401418454489501
doi:5184954083387691102
10.1001/5302954083346577107138173204225
jama.2009.1614.304710540831546103135148183216252286297327357387417429
PMID:349010540833588103148160
19903918.36641054083346498133166198230260273
55.30471153085367084
Weatherald314411540835790121142180214234267281320
J,347711540832436
Parhar35261154083356687125156177
KKS,371611540833571105117
Al384611540834156
Duhailib391611540834583120151166180195233
Z,416311540833750
Chu422611540834077114
DK,43541154083458094
Granholm44611154083446597134172209225282
A,475611540834154
Solverson48241154083327085117150171197235273
K,511011540833549
et517311540833355
al.52421154083314658
Efficacy5314115408332496785116149180213
of304712540833756
awake312012540833282114143177
prone33141254083385996133168
positioning349912540833876102117138153190228242280318
in383412540831452
patients39031254083387092106140178198225
with41451254083516687125
covid-1942871254083316799114152173203233
related45371254083215469100121154193
hypoxemic474712540833868107145175208265280311
respiratory50751254083205480118133153186207243264297
failure:538912540831851668011730471354083215466
systematic31261354083265884106139197228249264295
review34341354083215486101135185
and363213540833269107
meta‑analysis375213540835792113146167199236268282313340354379
of414413540833756
randomized42131354083205390128166223238266300338
trials.4564135408322435889103129142
BMJ.471913540833589114126
2022485813540833467100134
Dec500413540834680112
7;379:e071966.51291354083344378109142154188223255287316351386398
doi:30471454083387690102
10.1136/bmj-2022-071966.31631454083346576106133163196221260318332354384417450484503540572603633668703715
PMID:389214540833588103148160
36740866;406614540833568100130165200235270281
PMCID:436114540833588128143188200
PMC9727649.457514540833588128161193227259290326359369
56.30471553085367286
Ehrmann31471554083337090148179217254
S,341515540833244
Li347315540833146
J,353315540832435
Ibarra‑Estrada35821554083145385106127159181214241264284317355387
M,398215540835567
Perez40631554083356889122151
Y,422715540833643
Pavlov42841554083356697112150181
I,447815540831527
McNicholas451915540835486130145176213251266298323
B,485615540833547
et491715540833455
al;49861554083324758
Awake505715540834190123152185
Prone52561554083355592129164
Positioning5433155408335723047165408326406277114152166203242
Meta‑Trial330816540835489110142164194210225257271
Group.359816540834465102139178189
Awake380616540834191123152186
prone40111654083395996134168
positioning419816540833977103117139154191229243280319
for45361654083185576
COVID-19463116540834085120135181204234263
acute491316540833264101123156
hypoxaemic508816540833767107145174206241298312344
respiratory54511654083205430471754083266479100132153189210243
failure:3304175408319516680117138171183
a3501175408332
randomised,35471754083205290128166223238263297336348
controlled,390917540833168105126147183199213247286298
multinational,422117540835794109131145182214235250287325356371382
open‑label461717540833877111149171186218256291306
meta‑trial.493717540835792113145167189210225256270283
Lancet523417540833164101133166187
Respir54351754083367030471854083266479100
Med.316018540835489128140
2021331318540833468100131
Dec;9(12):1387-1395.345718540834580112124159177208238255266295324358390408438467500533545
doi:40151854083387690102
10.1016/S2213-2600(21)00356-8.41301854083346577107137169199223256288322353382403434467501537556589620633668703736768802824860872
Epub501618540833270108146
202151761854083346799130
Aug531918540834178116
20.54481854083346879
PMID:304719540833588103148160
34425070;322119540833469105137171205237269281
PMCID:351619540833588128143188200
PMC8378833.373019540833588128162195226259294327359371
57.30472053085367079
Rosén31412054083357399133171
J,332720540832435
von337720540833269106
Oelreich34992054083468196116150164196233
E,374720540833245
Fors38072054083326990116
D,393820540834656
Jonsson40092054083246299125151189226
Fagerlund425020540833361100134154170206244282
M,454720540835567
Taxbro46292054083336091130151187
K,483120540833549
Skorup48952054083336299120157196
P,510620540833539
et516020540833455
al;52302054083324758
PROFLO530320540833569117149179224
Study30472154083325289127158
Group.321621540834465101138176187
Awake341521540834089121150183
prone36102154083385995132166
positioning378721540833977102116138152189226241277315
in411421540831451
patients41762154083397191106139177197224
with44112154083506586124
hypoxemic454621540833767106143173206262277307
respiratory48652154083205379117132152184205240261294
failure5170215408319516579116136169
due535021540833875109
to547021540832157
COVID-19:304722540834085120135180203233263275
the33342254083225993
PROFLO343922540833570117150180225
multicenter367622540835794108130145176209246267300321
randomized40092254083205290128166223238266299338
clinical4359225408331466097112143175190
trial.4560225408322435889104116
Crit4688225408340607597
Care.47962254083407293126138
2021494522540833568100131
Jun50882254083246198
14;25(1):209.51982254083346576110144161192206217251285319330
doi:30472354083387690102
10.1186/s13054-021-03602-9.31632354083346576106133164198223246276305339372407429465498528546583615649684716736770780
PMID:395723540833588103148161
34127046;41312354083356999128160193228264275
PMCID:442023540833588128143188200
PMC8200797.463423540833588128162195228263295328360366
58.30472453085367186
Alhazzani31452454083415592124152183215252267
W,342324540835766
Parhar35012454083356686123155175
KKS,368824540833470104116
Weatherald381524540835790121142179213233265280318
J,414424540832435
Al419124540834155
Duhailib425824540834582119151165179194232
Z,450124540833850
Alshahrani45632454083405580117148186206238275289
M,486424540835466
Al‑Fares49422454083415576109138158191217
A,517124540834154
et523624540833456
al;53032454083324657
COVI­537224540833984119134156
‑PRONE30472554083215690136180212
Trial3270255408332486394108
Investigators33892554083145181114140161176213244265300321347
and374625540833269106
the38632554083215892
Saudi396625540833264100137151
Critical4128255408340607495110140172186
Care43252554083397191124
Trials4460255408332486293107132
Group.46032554083436399136174185
Effect47992554083325069102133156
of496625540833755
Awake503225540834189121149182
Prone52252554083355490127161
Positioning5397255408335709510930472654083213673110124161199
on325726540833775
Endotracheal334326540833269107144165186217249286319350365
Intubation37192654083155272109147179200214251288
in401926540831451
Patients40812654083356687101135172192219
With43112654083577394131
COVID-19445426540833983118134178201231260
and472526540833269107
Acute484326540834171108129162
Respiratory50162654083356995133148168200220256277310
Failure:5337265408332617589126146179190
A3047275408341
Randomized309927540833566103141178235249277310348
Clinical34582754083405468104118149181195
Trial.3664275408333496394109121
JAMA.379627540832462116157171
202239782754083346798132
Jun41212754083246197
7;327(21):2104-2113.42302754083334276107139154187217231242276306336371393423453480509520
doi:47612754083387589100
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PMID:304728540833588103148160
35569448;32212854083346799132165200237272283
PMCID:351828540833689128143188200
PMC9108999.373228540833588128161193223258292326361371
59.30472953085367083
Papazian314529540833566105137166181212249
L,341029540833144
Forel34692954083336990124138
JM,36232954083247891
Gacouin372929540834476107143181195232
A,397729540834154
Penot‑Ragon404629540833668106143164183220252290328365
C,442729540834052
Perrin44942954083356889110124162
G,467129540834456
Loundou474329540833168105142181218256
A,501429540834154
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al;51542954083324758
ACURASYS522729540834179123158200233269301
Study30473054083325390128160
Investigators.32243054083155283116142165179217249270306327354367
Neuromuscular360830540834579116136173230267293325362376408428
blockers40533054083395492124153186207234
in430430540831452
early43733054083346585100132
acute452230540833163100122155
respiratory46943054083215480119133154186207243264298
distress50093054083385278100121154180206
syndrome.52323054083275897135155192249284295
N3047315408345
Engl310631540833269108122
J3242315408324
Med.328031540835589128140
201034343154083346899130
Sep357831540833266105
16;363(12):1107-16.36973154083346476110144177195225255272283312339370402420450480493
doi:42043154083387590101
10.1056/NEJMoa1005372.43193154083356577107138171205229275307333387425457486517552586618650683695
PMID:502831540833588103148160
20843245.520231540833468102138170202233265276
60.30473253085367287
Price31503254083355570101134
DR,33003254083468194
Mikkelsen34103254083556999129163178203237275
ME,37013254083548799
Umscheid3816325408344101127158195230244282
CA,41143254083408296
Armstrong422632540834061119145167188224262300
EJ.45423254083335971
Neuromuscular462932540834479116136173230267293324361376407428
Blocking50733254083355088120149165202240
Agents532932540834179113150171198
and304733540833269107
Neuromuscular316633540834478115135172229266291323360374406426
Dysfunction360333540834678104123161198229253267304342
Acquired395633540834172109145160180213252
in421933540831552
Critical4282335408340607597111142175189
Illness:4483335408314294380114140166178
A4672335408341
Systematic47243354083336288110143200232253267298
Review503433540833569100115149200
and524533540833269107
Meta­536333540835589110142164
‑Analysis.30473454083216199131145176203217242255
Crit3318345408339607596
Care34303454083407292126
Med.357134540835589128140
201637273454083346798129
Nov;44(11):2070-2078.387134540834583114126160197215246273287298333366398430454484517549582595
doi:44813454083387690102
10.1097/CCM.0000000000001839.45983454083346577107138172204224262300354367402437473508543579614650685721756791823853886919929
PMID:304735540833588103148160
27513545.32213554083346799129158191225257268
61.30473653085366880
National31423654083457697112149187219233
Heart,339036540834478109130154166
Lung,357136540833167105143155
and374136540833269107
Blood38633654083355087125164
Institute40423654083155278100115136174195228
PETAL428536540833567101137169
Clinical44683654083405569106120152184198
Trials4681365408332496495110135
Network;483136540834479100153190211240254
Moss510036540835492118144
M,525836540835567
Huang534036540834481113150188
DT,30473754083457785
Brower31483754083365693143177197
RG,33623754083357992
Ferguson34703754083326686124161186224262
ND,374837540834590100
Ginde38643754083445996134169
AA,40493754083418397
Gong416237540834482120158
MN,433737540835499111
et446437540833456
al.45363754083324759
Early46123754083326485100131
Neuromuscular475937540834579117137174231268294325362377408429
Blockade52043754083365188120149182221255
in547537540831552
the30473854083225993
Acute315238540834172109131164
Respiratory33283854083356995134148169201222258279313
Distress36523854083466086108129162189214
Syndrome.387838540833362100138159195253287299
N4188385408345
Engl424538540833269108122
J4379385408324
Med.441538540835589128140
201945673854083346799128
May470738540835486116
23;380(21):1997-2008.48353854083346879113147181200234264278289318348382415432463496532566579
doi:54263854083387590101
10.1056/NEJMoa1901686.30473954083346577107138171205229274307333387424457486515550581612647681694
Epub375539540833271108147
201939163954083346798128
May405839540835486116
19.41883954083346474
PMID:427639540833588103148160
31112383;44503954083346491118148182215249259
PMCID:472339540833588128143188200
PMC6741345.493739540833588128161193223253282317349360
62.30474053085367186
Tsolaki31534054083335492107139168184
V,335640540833644
Zakynthinos342040540833770100133171192230244282320346
GE,37854054083447789
Papadonta389340540833667105138177214252273305
ME,421840540835487100
Bardaka43374054083356888126158187220
F,457640540833338
Fotakopoulos46334054083337091123153190229267305320357383
G,503640540834356
Pantazopoulos511140540833667105126158187224263301339353391417
I,304741540831527
et308941540833456
al.31604154083324659
Neuromuscular323441540834479116136173230267293324362376408428
Blockade36774154083365188120150182221255
in394741540831552
the40144154083225994
Pre-41234154083355588111
and424941540833269108
COVID-19437241540834084119135180203233263
ARDS465041540834176122154
Patients.48194154083356687102136173194221234
J5068415408324
Pers51084154083356888115
Med.523841540835489128140
2022539341540833468100134
Sep304742540833267105
19;12(9):1538.31664254083346476105135151183200212241270302336349
doi:35294254083387590101
10.3390/jpm12091538.36444254083346577112144177212236251289347376405439473505534566600613
PMID:427142540833588103148160
36143323;44454254083346897128160192224258269
PMCID:472742540833689129143188200
PMC9504585.494142540833588128161195228264296329363374
63.30474353085367084
Barbaro31434354083356787126157178214
RP,33684354083357074
Odetola345343540834685119140176191222
FO,36864354083327888
Kidwell37854354083355088138172186200
KM,399643540833590103
Paden411043540833566104137174
ML,42964354083548497
Bartlett44044354083356787111126159180204
RH,46194354083357991
Davis472143540834576107121146
MM,4879435408354107120
et501043540833455
al.50764354083324658
Association51454354083416893130162176207228242279316
of547243540833756
hospital‑level30474454083377399136150171202216237252285316348362
volume34204454083316781117173206
of363744540833654
extracorporeal37024454083336386106137168203223261298318351381395
membrane410844540835689145182203234270303
oxygenation44224454083376597134167204234255269305341
cases47744454083316287120145
and493044540833168105
mortality.504544540835793113137168182195216248257
Analysis531344540834076107121151177190215
of304745540833756
the31154554083215993
extracorporeal32204554083346589109142173209230269307328362393408
life3639455408315304882
support373345540832662101140178199223
organization39684554083375895127164179207240261275313350
registry.43304554083215493108133156176210219
Am456145540834198
J4671455408324
Respir47074554083367096134149169
Crit4888455408340617697
Care49974554083407293126
Med.513545540835589128140
201552874554083346899128
Apr542745540834180101
15;191(8):894-901.30474654083346373103132163178210228239273306341364398433464472
doi:35314654083387590101
10.1164/rccm.201409-1634OC.36444654083346577106133164199224242273303360372408441472502537572594625655688722770811823
PMID:447946540833588103148160
25695688;465046540833569102135169202237271283
PMCID:494446540833588128142187199
PMC4435456.515546540833588128160196228260294326360372
64.30474753085367388
Peek314747540833568103132
GJ,32914754083446980
Mugford338347540835492130149186207244
M,363947540835467
Tiruvoipati37184754083324969107139175190228261282296
R,402647540833649
Wilson40874754083577387112150188
A,428747540834054
Allen43534754083415570104141
E,450647540833345
Thalanany456347540833371103117149186218255285
MM,4860475408354109122
et499347540833456
al;50614754083324657
CESAR513047540834072105145180
trial5322475408322435889104
collaboration.5437475408332683047485408315296199137158191212226263301314
Efficacy3376485408332496785116149180213
and360448540833169107
economic372648540833466102140177235249281
assessment40214854083325884118144170227262299320
of435648540833756
conventional442648540833268106136170207228243280318349364
ventilatory480548540833165102123138152184205241262295
support511548540832663101140178199223
versus53534854083326586112149174
extracorporeal30474954083346588109141173209230269307328361393407
membrane347049540835791149187208240278312
oxygenation379749540833767100138172209241262277314352
for41644954083185576
severe42564954083266092125146179
adult445049540833270107122144
respiratory46094954083215480118133154186207243264297
failure4922495408318516580117137170
(CESAR):51084954083185789122162197215227
a5350495408332
multicentre53974954083579410930475054083223768101139160181215
randomised32815054083215491130168226240266301340
controlled364050540833168106127148185200215250289
trial.3948505408322435889104117
Lancet.408450540833165102134167189202
2009430550540833568104139
Oct446350540834780103
17;374(9698):1351-63.45855054083356473108139169188220255289324341353382412444475493530563575
doi:51795054083397791103
10.1016/53015054083356678108139171201226
S0140-6736(09)61069-2.30475154083326798128163187223255289323341374408426460489520555588611641653
Epub371651540833270108146
2009387851540833467103137
Sep403051540833367106
15.41515154083346475
Erratum42415154083335374106127165222
in:44785154083155263
Lancet.455751540833164101133166187200
2009477251540833468103138
Oct492551540834779102
17;374(9698):1330.50425154083356372107138168187218253286321338349378408440474485
PMID:304752540833588103148160
19762075.32215254083346496127160193225257269
65.30475353085367185
Combes315153540834076134173207234
A,340453540834154
Hajage34775354083447691122161195
D,369153540834555
Capellier376553540834073111146161175190224244
G,402853540834457
Demoule410453540834580137175213227261
A,438453540834155
Lavoué44585354083316495132170204
S,468153540833244
Guervilly474453540834482116137171186200215246
C,500953540834052
et508053540833456
al;51555354083324657
EOLIA523153540833380112126167
Trial5417535408332496495110
Group,304754540834465101139177188
REVA,325054540833568105143156
and342154540833169107
ECMONet.354254540833373127174219254275288
Extracorporeal38445454083336588109141173209230269307328361393407
Membrane426654540835488146184205237275309
Oxygenation458954540834778111149183221252273288325363
for49665454083195677
Severe50575454083336798132152186
Acute525754540834172109131164
Respiratory54355454083367030475554083266580101134156192214248
Distress33145554083466187110131165192218
Syndrome.355255540833262101140161198256291303
N3874555408346
Engl393955540833371110125
J4083555408325
Med.412755540835590130142
2018428955540833468100131
May443955540835688119
24;378(21):1965-1975.45775554083356678113145178197230262276287317347382416438468498531564575
doi:51725554083387691103
10.1056/52955554083346578108139173208232
NEJMoa1800385.304756540834577103157195227256287321357389423456467
PMID:352856540833588103148161
29791822.37035654083346799132163194227261272
66.30475753085367388
Shaefi314957540833270101135152169
S,333257540833345
Brenner33915754083355689127164198219
SK,36245754083326680
Gupta371857540834481120141173
S,390557540833345
O’Gara396457540834759102134155187
BP,41655754083367175
Krajewski42545754083355689103137188214243259
ML,45275754083548699
Charytan464057540834077108129162186218256
DM,4910575408345100112
et503657540833456
al;51065754083324657
STOP‑COVID517857540833266111147167209254289305350
Investigators.30475854083155283117143166180219250271308329356369
Extracorporeal34355854083326488109141173209230270308329362394409
membrane386358540835792149188209241279313
oxygenation419558540833867101139173211242263278316353
in456858540831452
patients46395854083397192107141179200227
with48855854083506587125
severe50295854083266192126147180
respiratory52295854083205480118133154186208244265298
failure3047595408318516580117137171
from32305954083183976134
COVID-19.337659540834084119135180203233263273
Intensive36615954083155273106143169183215248
Care39225954083407292125
Med.406059540835488127140
2021421259540833467100130
Feb;47(2):208-221.435459540833366105116150182197230248259293327361383414448478487
doi:48535954083387691102
10.1007/s00134-02006331-9.49675954083346577107138173205224248282318349378413435471504537304760540833469102135165183217227
Epub328860540833371108147
2021344960540833467100130
Feb359360540833366104
2.371160540833546
PMID:377160540833588103148161
33528595;39466054083346698131164197229262272
PMCID:423260540833588128142187200
PMC7851810.444660540833588128162195228258289320351363
67.30476153085367078
Whebell313861540835796130168203218232
S,338361540833244
Zhang344061540833875106144182
J,363461540832536
Lewis368261540833265116131156
R,385061540833649
Berry39126154083356990111144
M,406961540835467
Ledot414861540833265104142163
S,432361540833345
Retter43806154083367091115148169
A,456161540834154
et462861540833455
al.46966154083324659
Survival47676154083336990124139171203218
benefit499761540833973111145162179201
of521061540833756
extracorporeal5278615408334658911014217321023030476254083397798131162177
membrane323862540835892149188209241278313
oxygenation356562540833767100138172209241262277314352
in393162540831552
severe39976254083266192126146180
COVID-19:419162540834085120136181204234263276
a4481625408332
multi‑centre‑matched452762540835895109131146167200233270291312345368426457478508546580619
cohort516062540833268106143164188
study.53636254083264885124155164
Intensive30476354083155273106143169183215249
Care33136354083407293126
Med.345763540835589128140
2022361563540833468100134
Apr;48(4):467-478.376763540834179100113147182200233249261294330362380416447480492
doi:42776354083387691102
10.1007/s00134-022-06645-w.43976354083346577107137173205224248282317348378412435471503537557594629663699731753804814
Epub522963540833271108146
2022539363540833468100134
Mar304764540835486107
3.316864540833446
Erratum32286454083325273106127164221
in:34636454083155263
Intensive35406454083155273106144169183215249
Care38036454083407292126
Med.394264540835589128141
202240976454083346799133
Mar424464540835587107
18:43656454083346476
PMID:445564540833588103148160
35238946;46296454083346799133167201236271283
PMCID:492664540833588128142187199
PMC8892395.513964540833588128162197230263297329363374
68.30476553085367388
Bein31516554083357084121
T,328865540833341
Weber‑Carstens334565540835890128163184203245277298324347380417443
S,380465540833244
Goldmann38646554083448297135193224262299
A,417965540834154
Müller424965540835592106121155175
T,444065540833341
Staudinger44976554083335385122160175212250284305
T,481865540833241
Brederlau48756554083355689128162182198229266
J,515765540832435
et520865540833456
al.52806554083324659
Lower535565540833168118152172
tidal30476654083223674106121
volume31846654083316883120177212
strategy34126654083264869101122155194226
(≈336546654083185890
ml/kg)37556654083577297127164182
combined395366540833268125164179216250289
with42586654083516587125
extracorporeal43996654083346588109141173209230269307328361392407
CO2482266540834085116
removal495566540832054111148180212227
versus51986654083316585112148174
‚conventional’53886654083124480118304767540833266105126141179217250265278
protective33456754083396098119153186210225257292
ventilation365667540833267105126141156188210225263301
(6397767540831952
ml/kg)40416754083587399130168186
in424767540831552
severe43196754083276294128149183
ARDS:452267540834177124156168
the47096754083226196
prospective48246754083396198125164199232256271304338
randomized51816754083215493132170229243272306346
Xtravent‑study.30476854083385879111142175213234253279301339377408418
Intensive34796854083145272106143169183215248
Care37416854083407293126
Med.388168540835589128140
201340356854083356899128
May;39(5):847-56.417768540835587117129164196215247265276310346377395429462475
doi:46666854083387590102
10.1007/s00134-012-2787-6.47826854083346576107137173205224248282317348377412434471502531551581613646678696733745
Epub304769540833371108147
201332086954083346798128
Jan33496954083255693
10.34566954083346577
PMID:354769540833588103148160
23306584;372169540833569101135170203236272283
PMCID:401869540833588128142187200
PMC3625408.423269540833588128163196229263298333368380
69.30477053085367184
McNamee314970540835486130162219254288
JJ,34557054083244759
Gillies3532705408343587387101135161
MA,371170540835596109
Barrett38387054083356888109142164188
NA,40437054083458699
Perkins41607054083356888118134171197
GD,437470540834489100
Tunnicliffe449170540833366103140155186201215234253286
W,479570540835867
Young487970540833669106144182
D,507970540834555
et515270540833456
al;52257054083324758
REST530170540833568101135
Investigators.54547054083145230477154083326591114128167198219255276303316
Effect33797154083335170104136159
of355571540833756
Lower362771540833268119152173
Tidal38177154083324886118133
Volume39667154083367187123181215
Ventilation419871540833567105125140155186207222259297
Facilitated45117154083336193107122136158190211244283
by481071540833970
Extracorporeal48967154083336588109141173209230269307328361393407
Carbon53207154083407292131170207
Dioxide30477254083456097127142180214
Removal327972540833570127165196228243
vs354072540833157
Standard36157254083335385123161193213250
Care38837254083407293126
Ventilation402772540833668105126141155187208222259297
on434272540833775
90-Day44357254083346992139170200
Mortality465372540835592113137169184198220253
in492472540831553
Patients49967254083356789104139177199226
With52417254083587496135
Acute539572540834172110304773540832256
Hypoxemic312373540834476116155186220278293326
Respiratory34697354083367198137152174207229266287322
Failure:3811735408333627793130152186198
The403073540833372107
REST415873540833569103138
Randomized431673540833669107146184243258287321361
Clinical46987354083405570108123155188204
Trial.4922735408333506698114127
JAMA.506973540832565120163177
2021526773540833468101133
Sep542173540833267107
21;326(11):1013-1023.30477454083346674109141175194226253268280309341373403424455487520554567
doi:36287454083387692104
10.1001/jama.2021.13374.37467454083346678109141177209230247279336369382418452485517526557587620652682695
Erratum44557454083325375108130168226
in:46957454083155265
JAMA.477474540832464120161176
2022496474540833569102136
Jan51157454083245694
4;327(1):86.52237454083344681114147163195209221256291305
PMID:304775540833589104150163
34463700;322675540833469106142176208241277290
PMCID:353175540833689130145191204
PMC8408762.375075540833589129164200236272305337370382