Anest. intenziv. Med. 2026;37(2):101-105 | DOI: 10.36290/aim.2026.013

Dynamic arterial elastance - current perspectivesReview Article

Klimovič A.^1-3, Smékalová O.^1-4, Kletečka J.^1-2, Beneš J.^{1-3, 5}, Zatloukal J.^1-3

¹ Klinika anesteziologie, resuscitace a intenzivní medicíny, Lékařská fakulta v Plzni, Univerzita Karlova

² Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Plzeň

³ Simulační centrum Plzeň (SIM/PL), Lékařská fakulta v Plzni, Univerzita Karlova

⁴ Ústav simulační medicíny, Lékařská fakulta Masarykovy univerzity, Brno

⁵ Biomedicínské centrum, Lékařská fakulta v Plzni, Univerzita Karlova

Arterial hypotension is a major risk factor for morbidity and mortality in perioperative and intensive care settings. However, an increase in cardiac output after a fluid challenge does not always result in a corresponding rise in arterial blood pressure, reflecting the complex interaction between cardiac output and the arterial system. Dynamic arterial elastance, defined as the ratio of pulse pressure variation to stroke volume variation, has been proposed as a functional parameter describing the ability of the arterial system to translate changes in cardiac output into changes in arterial pressure. Eadyn thus represents a parameter capable of predicting the arterial pressure response to an increase in cardiac output following preload augmentation. The aim of this narrative review is to summarize current knowledge on the physiological basis of dynamic arterial elastance, the methodology of its measurement, its limitations, and its potential clinical applications.

Keywords: dynamic arterial elastance, intensive care medicine, perioperative medicine, cardiovascular system.

Received: March 30, 2026; Revised: March 30, 2026; Accepted: April 15, 2026; Prepublished online: June 8, 2026; Published: July 10, 2026  Show citation